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Ordino:一种用于对基因、细胞系和组织样本进行排名和探索的可视化癌症分析工具。

Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines and tissue samples.

作者信息

Streit Marc, Gratzl Samuel, Stitz Holger, Wernitznig Andreas, Zichner Thomas, Haslinger Christian

机构信息

Institute of Computer Graphics, Johannes Kepler University Linz, Linz A-4040, Austria.

datavisyn GmbH, Linz A-4020, Austria.

出版信息

Bioinformatics. 2019 Sep 1;35(17):3140-3142. doi: 10.1093/bioinformatics/btz009.

Abstract

SUMMARY

Ordino is a web-based analysis tool for cancer genomics that allows users to flexibly rank, filter and explore genes, cell lines and tissue samples based on pre-loaded data, including The Cancer Genome Atlas, the Cancer Cell Line Encyclopedia and manually uploaded information. Interactive tabular data visualization that facilitates the user-driven prioritization process forms a core component of Ordino. Detail views of selected items complement the exploration. Findings can be stored, shared and reproduced via the integrated session management.

AVAILABILITY AND IMPLEMENTATION

Ordino is publicly available at https://ordino.caleydoapp.org. The source code is released at https://github.com/Caleydo/ordino under the Mozilla Public License 2.0.

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

摘要

Ordino是一款基于网络的癌症基因组学分析工具,它允许用户根据预加载的数据(包括癌症基因组图谱、癌细胞系百科全书和手动上传的信息)灵活地对基因、细胞系和组织样本进行排名、筛选和探索。交互式表格数据可视化有助于用户驱动的优先级排序过程,是Ordino的核心组成部分。所选项目的详细视图对探索起到补充作用。研究结果可以通过集成的会话管理进行存储、共享和再现。

可用性与实现方式

Ordino可在https://ordino.caleydoapp.org上公开获取。源代码在https://github.com/Caleydo/ordino上根据Mozilla公共许可证2.0发布。

补充信息

补充数据可在《生物信息学》在线版获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bb/6736116/8d3be272ac66/btz009f1.jpg

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