网状 Meta 分析结局汇总表的制定。
Development of the summary of findings table for network meta-analysis.
机构信息
Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; School of Medicine, Universidad de los Andes, Carrera 7 No. 116 - 05, Bogotá, D.C., Colombia.
University of Toronto, 155 College Street, Toronto, Ontario, Canada.
出版信息
J Clin Epidemiol. 2019 Nov;115:1-13. doi: 10.1016/j.jclinepi.2019.04.018. Epub 2019 May 2.
OBJECTIVES
The aim of the study was to develop a Grading of Recommendations, Assessment, Development and Evaluation (GRADE) summary of findings (SoF) table format that displays the critical information from a network meta-analysis (NMA).
STUDY DESIGN AND SETTING
We applied a user experience model for data analysis based on four rounds of semistructured interviews.
RESULTS
We interviewed 32 stakeholders who conduct or use MA. Four rounds of interviews produced six candidate NMA-SoF tables. Users found a final NMA-SoF table that included the following components highly acceptable: (1) details of the clinical question (PICO), (2) a plot depicting network geometry, (3) relative and absolute effect estimates, (4) certainty of evidence, (5) ranking of treatments, and (6) interpretation of findings.
CONCLUSION
Using stakeholder feedback, we developed a new GRADE NMA-SoF table that includes the relevant components that facilitate understanding NMA findings and health decision-making.
目的
本研究旨在开发一种分级评估、制定与评价（GRADE）总结报告（SoF）表格格式，以展示网络荟萃分析（NMA）的关键信息。
研究设计和设置
我们基于四轮半结构化访谈，应用数据分析用户体验模型。
结果
我们采访了 32 名进行或使用 MA 的利益相关者。四轮访谈产生了六个候选 NMA-SoF 表格。用户对包含以下组件的最终 NMA-SoF 表格高度认可：（1）临床问题（PICO）的详细信息，（2）描绘网络几何形状的图表，（3）相对和绝对效果估计，（4）证据确定性，（5）治疗方案排名，以及（6）研究结果解释。
结论
通过利益相关者的反馈，我们开发了一种新的 GRADE NMA-SoF 表格，其中包含有助于理解 NMA 结果和健康决策的相关组件。
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