美国特应性皮炎的管理挑战
The Challenge of Managing Atopic Dermatitis in the United States.
作者信息
Feldman Steven R, Cox Linda S, Strowd Lindsay C, Gerber Robert A, Faulkner Steven, Sierka Debra, Smith Timothy W, Cappelleri Joseph C, Levenberg Mark E
机构信息
Professor of Dermatology, Pathology, and Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Practicing Physician, Adult and Pediatric Allergy and Immunology Practice, and is Assistant Clinical Professor of Medicine, University of Miami School of Medicine and Nova Southeastern University School of Osteopathic Medicine, Ft Lauderdale, FL.
出版信息
Am Health Drug Benefits. 2019 Apr;12(2):83-93.
BACKGROUND
Atopic dermatitis is a chronic inflammatory skin disease that affects up to 13% of children and 10% of adults in the United States. Among patients and their families, atopic dermatitis has a considerable effect on quality of life and represents a substantial economic burden.
OBJECTIVE
To describe the impact and challenges of atopic dermatitis and to provide nondermatologists in the healthcare community an enhanced understanding of atopic dermatitis to facilitate treatment and pharmacy benefit discussions.
DISCUSSION
Atopic dermatitis is a heterogeneous disease, and its diagnosis is hampered by a lack of objective diagnostic criteria. The current management guidelines address the distinct clinical phenotypes as a single disease and do not incorporate recent clinical advances, such as the targeting of specific inflammatory processes. The treatment guidelines for atopic dermatitis are complex and challenge healthcare providers, patients, and caregivers. Novel treatments can provide additional therapeutic options for patients with atopic dermatitis.
CONCLUSIONS
Treatment options for atopic dermatitis are expanding with the development of novel anti-inflammatory therapies. An increased understanding of these advancements is necessary to optimize care for patients with atopic dermatitis.
背景
特应性皮炎是一种慢性炎症性皮肤病，在美国影响着高达13%的儿童和10%的成年人。在患者及其家庭中，特应性皮炎对生活质量有相当大的影响，并构成了沉重的经济负担。
目的
描述特应性皮炎的影响和挑战，并使医疗保健社区中的非皮肤科医生更好地了解特应性皮炎，以促进治疗和药物福利讨论。
讨论
特应性皮炎是一种异质性疾病，缺乏客观诊断标准阻碍了其诊断。当前的管理指南将不同的临床表型视为单一疾病，并未纳入近期的临床进展，如针对特定炎症过程的治疗。特应性皮炎的治疗指南复杂，给医疗保健提供者、患者和护理人员带来了挑战。新型治疗方法可为特应性皮炎患者提供更多治疗选择。
结论
随着新型抗炎疗法的发展，特应性皮炎的治疗选择正在不断扩大。有必要更多地了解这些进展，以优化对特应性皮炎患者的护理。
Zotero 插件