Memorial Sloan Kettering Cancer Center.
Roswell Park Comprehensive Cancer Center.
J Natl Compr Canc Netw. 2019 Jun 1;17(6):721-749. doi: 10.6004/jnccn.2019.0028.
Acute myeloid leukemia (AML) is the most common form of acute leukemia among adults and accounts for the largest number of annual deaths due to leukemias in the United States. Recent advances have resulted in an expansion of treatment options for AML, especially concerning targeted therapies and low-intensity regimens. This portion of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for AML focuses on the management of AML and provides recommendations on the workup, diagnostic evaluation and treatment options for younger (age <60 years) and older (age ≥60 years) adult patients.
急性髓系白血病(AML)是成年人中最常见的急性白血病类型,也是美国因白血病导致的年度死亡人数最多的疾病。最近的进展使得 AML 的治疗选择得到了扩展,特别是在靶向治疗和低强度治疗方案方面。NCCN 肿瘤临床实践指南(NCCN 指南)中关于 AML 的这一部分侧重于 AML 的管理,并就年龄<60 岁和年龄≥60 岁的成年患者的 AML 检查、诊断评估和治疗选择提供建议。