通过. 的生物转化生成具有农业化学意义的吲哚
Generation of Indoles with Agrochemical Significance through Biotransformation by .
机构信息
College of Plant Protection, State & Local Joint Engineering Research Center of Green Pesticide Invention and Application , Nanjing Agricultural University , Nanjing 210095 , People's Republic of China.
State Key Laboratory Cultivation Base for TCM Quality and Efficacy , Nanjing University of Chinese Medicine , Nanjing 210023 , People's Republic of China.
出版信息
J Nat Prod. 2019 Aug 23;82(8):2132-2137. doi: 10.1021/acs.jnatprod.8b01101. Epub 2019 Jul 22.
Six new (-) and two known ( and ) indole alkaloids were produced by the marine fish-derived fungus 1C51 through biotransformation. The structures of these alkaloids were elucidated by a combination of MS, NMR, and X-ray crystallography analyses. Chaetoindolone A () was shown to inhibit the growth of the rice-pathogenic bacteria pv. () both in vitro and in vivo. Chaetogline A () was found to be fungicidal against , a pathogen causing rape sclerotinia rot. Collectively, this work provides access to new indole alkaloids with potential agrochemical significance.
海洋鱼类来源的真菌 1C51 通过生物转化生成了 6 种新的（-）和 2 种已知（和）吲哚生物碱。这些生物碱的结构通过 MS、NMR 和 X 射线晶体学分析的组合来阐明。Chaetoindolone A () 被证明在体外和体内均能抑制水稻病原菌 pv. () 的生长。Chaetogline A () 对引起油菜菌核腐烂的病原菌具有杀菌作用。总的来说，这项工作提供了具有潜在农业化学意义的新吲哚生物碱。
Zotero 插件