Jilin Provincial Key Laboratory on Molecular and Chemical Genetics, The Second Hospital of Jilin University, Changchun 130041, China.
Department of Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
Biomed Res Int. 2019 Aug 14;2019:5763602. doi: 10.1155/2019/5763602. eCollection 2019.
Dioscin is a typical saponin with multiple pharmacological activities. The past few years have seen an emerging interest in and growing research on this pleiotropic saponin. Here, we review the emerging pharmacological activities reported recently, with foci on its antitumor, antimicrobial, anti-inflammatory, antioxidative, and tissue-protective properties. The potential use of dioscin in therapies of diverse clinical disorders is also discussed.
薯蓣皂苷元是一种具有多种药理活性的典型皂苷。近年来,人们对这种多效性皂苷的兴趣日益浓厚,研究也日益增多。本文综述了其近年来报道的新兴药理活性,重点介绍了其抗肿瘤、抗菌、抗炎、抗氧化和组织保护作用。还讨论了薯蓣皂苷元在治疗多种临床疾病中的潜在用途。