Division of Cardiac Surgery, Department of Surgery, University of Virginia Health System, Charlottesville, Va.
Division of Cardiothoracic Surgery, Department of Surgery, University of Arizona College of Medicine, Tucson, Ariz.
J Thorac Cardiovasc Surg. 2020 Jun;159(6):2326-2335.e3. doi: 10.1016/j.jtcvs.2019.08.032. Epub 2019 Sep 9.
To determine trends in National Institutes of Health (NIH) funding for cardiac surgeons, hypothesizing they are at a disadvantage in obtaining funding owing to intensive clinical demands.
Cardiac surgeons (adult/congenital) currently at the top 141 NIH-funded institutions were identified using institutional websites. The NIH funding history for each cardiac surgeon was queried using the NIH Research Portfolio Online Reporting Tools Expenditures and Results (RePORTER). Total grant funding, publications, and type was collected. Academic rank, secondary degrees, and fellowship information was collected from faculty pages. Grant productivity was calculated using a validated grant impact metric.
A total of 818 academic cardiac surgeons were identified, of whom 144 obtained 293 NIH grants totaling $458 million and resulting in 6694 publications. We identified strong associations between an institution's overall NIH funding rank and the number of cardiac surgeons, NIH grants to cardiac surgeons, and amount of NIH funding to cardiac surgeons (P < .0001 for all). The majority of NIH funding to cardiac surgeons is concentrated in the top quartile of institutions. Cardiac surgeons had a high conversion rates from K awards (mentored development awards) to R01s (6 of 14; 42.9%). Finally, we demonstrate that the rate of all NIH grants awarded to cardiac surgeons has increased, driven primarily by P and U (collaborative project) grants.
NIH-funded cardiac surgical research has had a significant impact over the last 3 decades. Aspiring cardiac surgeon-scientists may be more successful at top quartile institutions owing to better infrastructure and mentorship.
确定美国国立卫生研究院(NIH)对心脏外科医生资助的趋势,假设由于临床需求的增加,他们在获得资助方面处于不利地位。
使用机构网站确定目前在排名前 141 的 NIH 资助机构工作的心脏外科医生(成人/先天性)。使用 NIH 研究组合在线报告工具支出和结果(RePORTER)查询每位心脏外科医生的 NIH 资助历史。收集了总赠款资金、出版物和类型。从教员页面收集学术职称、副学位和奖学金信息。使用经过验证的赠款影响指标计算赠款生产力。
共确定了 818 名学术心脏外科医生,其中 144 人获得了 293 项 NIH 资助,共计 4.58 亿美元,产生了 6694 篇论文。我们发现,机构 NIH 总体资助排名与心脏外科医生数量、NIH 授予心脏外科医生的资助以及 NIH 授予心脏外科医生的资金数量之间存在很强的关联(所有 P <.0001)。大多数 NIH 资助给心脏外科医生的资金集中在排名前四分之一的机构。心脏外科医生从 K 奖(导师发展奖)转为 R01 奖(14 人中的 6 人;42.9%)的转化率很高。最后,我们证明授予心脏外科医生的所有 NIH 资助的比例一直在增加,主要是由 P 和 U(合作项目)资助推动的。
在过去的 30 年里,NIH 资助的心脏外科研究产生了重大影响。有抱负的心脏外科医生-科学家可能在排名前四分之一的机构中更成功,因为那里有更好的基础设施和指导。