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代谢和减重手术 30 天结局的种族差异。

Racial Disparity in 30-Day Outcomes of Metabolic and Bariatric Surgery.

机构信息

Graduate College, Rush University, Chicago, IL, USA.

Division of Minimally Invasive and Bariatric Surgery, Rush University Medical Center, 1653 W. Congress Pkwy, Jelke Building, Suite 604, Chicago, IL, 60612, USA.

出版信息

Obes Surg. 2020 Mar;30(3):1011-1020. doi: 10.1007/s11695-019-04282-9.

Abstract

BACKGROUND

There is evidence of racial disparity in the long-term weight loss outcomes of bariatric surgery. However, there has been a more limited evaluation of the impact of race on immediate perioperative outcomes. The aim of this study was to compare 30-day postoperative outcomes among different races.

STUDY DESIGN

The 2016 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database was queried to identify patients aged ≥ 18 and body mass index ≥ 35 who underwent primary laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG) with known information on race. We then evaluated the effect of five different races on four different 30-day outcomes.

RESULTS

Of the total 106,932 patients (79.5% White, 19.3% African American (AA), 0.5% Asian, 0.4% American Indian or Alaska Native, 0.3% Native Hawaiian or other Pacific Islander), 30-day rates of postoperative complication, readmission, re-intervention, and reoperation were 6, 3.8, 1.3, and 1.2%, respectively. After controlling for other covariates in multivariate logistic regression and selecting White as reference, AA was the only race associated with a higher risk of postoperative complications (odds ratio [OR] 1.13; confidence interval [CI] 1.06-1.2) and readmissions (OR 1.47; CI 1.3-1.6). AA and American Indian or Alaska Native were also associated with higher re-interventions (OR 1.31; CI 1.15-1.51 and OR 2.11; CI 1.03-4.34). Furthermore, AA was associated with lower 30-day reoperations (OR 0.83; CI 0.7-0.9).

CONCLUSION

This study found significant racial differences in short-term outcomes following bariatric surgery. Factors underlying these disparities are unclear and warrant further investigation.

摘要

背景

减重手术的长期减重效果存在种族差异的证据。然而,对于种族对围手术期即刻结果的影响,评估的范围则较为有限。本研究旨在比较不同种族患者术后 30 天的结果。

研究设计

查询 2016 年代谢和减重手术认证和质量改进计划(MBSAQIP)数据库,以确定年龄≥18 岁、体重指数≥35 且行腹腔镜下 Roux-en-Y 胃旁路术(LRYGB)或腹腔镜袖状胃切除术(LSG)的患者,并明确种族信息。然后,我们评估了 5 种不同种族对 4 种不同术后 30 天结局的影响。

结果

在总计 106932 例患者中(79.5%为白人,19.3%为非裔美国人(AA),0.5%为亚裔,0.4%为美洲印第安人或阿拉斯加原住民,0.3%为夏威夷原住民或其他太平洋岛民),术后并发症、再入院、再干预和再次手术的 30 天发生率分别为 6%、3.8%、1.3%和 1.2%。在校正了多变量逻辑回归中的其他协变量,并选择白人作为参照后,AA 是唯一与术后并发症(比值比[OR]1.13;95%置信区间[CI]1.06-1.2)和再入院(OR 1.47;95%CI 1.3-1.6)风险增加相关的种族。AA 和美洲印第安人或阿拉斯加原住民也与再干预(OR 1.31;95%CI 1.15-1.51 和 OR 2.11;95%CI 1.03-4.34)的风险增加相关。此外,AA 与术后 30 天再次手术(OR 0.83;95%CI 0.7-0.9)的风险降低相关。

结论

本研究发现减重手术后短期结局存在显著的种族差异。这些差异的根本原因尚不清楚,需要进一步研究。

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本文引用的文献

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