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突破:磷酸氯喹在临床研究中显示出对 COVID-19 相关肺炎的明显疗效。

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies.

机构信息

Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, China.

Department of Pharmacy, Qingdao Municipal Hospital, Qingdao, China.

出版信息

Biosci Trends. 2020 Mar 16;14(1):72-73. doi: 10.5582/bst.2020.01047. Epub 2020 Feb 19.

Abstract

The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China for treatment of COVID-19 infection in larger populations in the future.

摘要

新型冠状病毒肺炎(COVID-19)疫情迅速蔓延,中国科学家正努力寻找有效的治疗药物。磷酸氯喹是一种治疗疟疾的老药,在中国进行的多中心临床试验显示对 COVID-19 相关肺炎有明显疗效和可接受的安全性。建议将该药纳入国家卫生健康委员会发布的《新型冠状病毒肺炎诊疗方案》(试行第七版),未来用于更大规模的 COVID-19 感染人群。

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