生活方式医学中的精准医学：未来之路？
Precision Medicine in Lifestyle Medicine: The Way of the Future?
作者信息
Gray Ian D, Kross Andrea R, Renfrew Melanie E, Wood Paul
机构信息
Avondale College of Higher Education, Cooranbong, New South Wales, Australia.
出版信息
Am J Lifestyle Med. 2019 Mar 20;14(2):169-186. doi: 10.1177/1559827619834527. eCollection 2020 Mar-Apr.
Abstract
Precision medicine has captured the imagination of the medical community with visions of therapies precisely targeted to the specific individual's genetic, biological, social, and environmental profile. However, in practice it has become synonymous with genomic medicine. As such its successes have been limited, with poor predictive or clinical value for the majority of people. It adds little to lifestyle medicine, other than in establishing why a healthy lifestyle is effective in combatting chronic disease. The challenge of lifestyle medicine remains getting people to actually adopt, sustain, and naturalize a healthy lifestyle, and this will require an approach that treats the patient as a person with individual needs and providing them with suitable types of support. The future of lifestyle medicine is holistic and person-centered rather than technological.
摘要
精准医学以针对个体特定的基因、生物、社会和环境特征的精准疗法愿景，激发了医学界的想象力。然而，在实践中，它已成为基因组医学的代名词。因此，其成功有限，对大多数人而言预测价值或临床价值不佳。除了能确定健康生活方式为何对对抗慢性病有效外，它对生活方式医学的贡献不大。生活方式医学面临的挑战仍然是促使人们真正采用、维持并将健康生活方式融入日常生活，而这需要一种将患者视为有个体需求的人并为其提供合适支持类型的方法。生活方式医学的未来是整体的、以患者为中心的，而非技术导向的。
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