Department of Otolaryngology-Head and Neck Surgery, University of Minnesota Medical School, 516 Delaware Street Southeast, # 8A, Minneapolis, MN 55455, USA.
Department of Otorhinolaryngology-Head & Neck Surgery, McGovern Medical School at the University of Texas Health Science Center, Texas Sinus Institute, 6431 Fannin Street, MSB 5.036, Houston, TX 77030, USA; Center for Immunology and Autoimmune Diseases, Institute of Molecular Medicine, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA.
Immunol Allergy Clin North Am. 2020 May;40(2):345-359. doi: 10.1016/j.iac.2019.12.001. Epub 2020 Jan 29.
Allergic fungal rhinosinusitis (AFRS) represents a subtype of chronic rhinosinusitis with nasal polyposis that exhibits a unique, often striking clinical presentation. Since its initial description more than a quarter century ago, a more sophisticated understanding of the pathophysiology of AFRS has been achieved and significant advancements in improving clinical outcomes made. This review focuses on the latest developments involving the pathophysiology and clinical management of this fascinating disease.
变应性真菌性鼻鼻窦炎(AFRS)是一种具有鼻息肉的慢性鼻-鼻窦炎的亚型,具有独特的、常常引人注目的临床表现。自 25 年前首次描述以来,对 AFRS 的病理生理学有了更深入的了解,并在改善临床结局方面取得了重大进展。本综述重点介绍了该迷人疾病的病理生理学和临床管理方面的最新进展。