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新冠肺炎中抗体反应欠佳的潜在危险。

The potential danger of suboptimal antibody responses in COVID-19.

机构信息

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

Howard Hughes Medical Institute, Chevy Chase, MD, USA.

出版信息

Nat Rev Immunol. 2020 Jun;20(6):339-341. doi: 10.1038/s41577-020-0321-6.

Abstract

There is a desperate need for effective therapies and vaccines for SARS-CoV-2 to mitigate the growing economic crisis that has ensued from societal lockdown. Vaccines are being developed at an unprecedented speed and are already in clinical trials, without preclinical testing for safety and efficacy. Yet, safety evaluation of candidate vaccines must not be overlooked.

摘要

非常需要针对 SARS-CoV-2 的有效疗法和疫苗来减轻因社会封锁而导致的日益严重的经济危机。疫苗的研发速度前所未有,已经进入临床试验阶段,而没有进行临床前的安全性和有效性测试。然而,候选疫苗的安全性评估不容忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3dc/7187142/31f1dc8423a5/41577_2020_321_Fig1_HTML.jpg

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