硒和硒蛋白对家禽和猪免疫反应的影响。
The influence of selenium and selenoproteins on immune responses of poultry and pigs.
作者信息
Dalgaard Tina S, Briens Mickaël, Engberg Ricarda M, Lauridsen Charlotte
机构信息
Dept. of Animal Science, Aarhus University, Blichers allé 20, 8830 Tjele, Denmark.
Adisseo France, CERN, 6 Route Noire, 03600 Commentry, France.
出版信息
Anim Feed Sci Technol. 2018 Apr;238:73-83. doi: 10.1016/j.anifeedsci.2018.01.020. Epub 2018 Jan 31.
Selenium is an essential nutrient for poultry and pigs, and is important for a number of physiological processes including regulation and function of the immune system. Through its incorporation into selenoproteins, Se is involved in the regulation of oxidative stress, redox mechanisms, and other crucial cellular processes involved in innate and adaptive immune response. This review provides current knowledge on the mechanisms by which selenium can modulate the resilience to infectious diseases, and how this micronutrient can influence the capacity of the bird or the pig to maintain its productivity during an infectious challenge. In relation to the most frequent and economically important infectious diseases in poultry and pig production, the present paper considers the influence of different selenium sources (organic inorganic Se) as well as dietary concentrations on the immune responses of poultry and pigs with major emphasis on the potential beneficial impact on animal resilience to common infectious diseases.
硒是家禽和猪必需的营养素，对包括免疫系统调节和功能在内的许多生理过程都很重要。通过掺入硒蛋白，硒参与氧化应激、氧化还原机制以及先天和适应性免疫反应中涉及的其他关键细胞过程的调节。本综述提供了关于硒调节对传染病恢复力的机制的当前知识，以及这种微量营养素如何影响禽类或猪在感染挑战期间维持其生产力的能力。关于家禽和猪生产中最常见且具有经济重要性的传染病，本文考虑了不同硒源（有机硒和无机硒）以及日粮浓度对家禽和猪免疫反应的影响，主要强调对动物抵抗常见传染病的潜在有益影响。
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