从 COVID-19 患者尿液中分离出传染性 SARS-CoV-2。
Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient.
机构信息
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, People's Republic of China.
出版信息
Emerg Microbes Infect. 2020 Dec;9(1):991-993. doi: 10.1080/22221751.2020.1760144.
SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated could infect new susceptible cells and was recognized by its' own patient sera. Appropriate precautions should be taken to avoid transmission from urine.
严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）引起人类严重肺炎（COVID-19）的大爆发。在 COVID-19 患者的多个器官中检测到病毒 RNA。然而，传染性 SARS-CoV-2 仅从呼吸道标本中分离。在此，从一名 COVID-19 患者的尿液中成功分离到传染性 SARS-CoV-2。分离出的病毒可以感染新的易感细胞，并被其自身的患者血清识别。应采取适当的预防措施，避免从尿液中传播。
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