轻症与重症 COVID-19：实验室标志物。
Mild versus severe COVID-19: Laboratory markers.
机构信息
Institute of Tropical Medicine, Universitätsklinikum Tübingen, Germany; Vietnamese German Center for Medical Research, Hanoi, Vietnam; Faculty of Medicine, Duy Tan University, Da Nang, Vietnam.
Institute of Tropical Medicine, Universitätsklinikum Tübingen, Germany; Vietnamese German Center for Medical Research, Hanoi, Vietnam; Faculty of Medicine, Duy Tan University, Da Nang, Vietnam.
出版信息
Int J Infect Dis. 2020 Jun;95:304-307. doi: 10.1016/j.ijid.2020.04.061. Epub 2020 Apr 25.
The number of COVID-19 patients is dramatically increasing worldwide. Treatment in intensive care units (ICU) has become a major challenge; therefore, early recognition of severe forms is absolutely essential for timely triaging of patients. While the clinical status, in particular peripheral oxygen saturation (SpO2) levels, and concurrent comorbidities of COVID-19 patients largely determine the need for their admittance to ICUs, several laboratory parameters may facilitate the assessment of disease severity. Clinicians should consider low lymphocyte count as well as the serum levels of CRP, D-dimers, ferritin, cardiac troponin and IL-6, which may be used in risk stratification to predict severe and fatal COVID-19 in hospitalised patients. It is more likely that the course of the disease will be unfavourable if some or all of these parameters are altered.
全球范围内 COVID-19 患者数量正在急剧增加。在重症监护病房（ICU）进行治疗已成为一项重大挑战；因此，及早识别严重形式对于及时对患者进行分诊至关重要。虽然 COVID-19 患者的临床状况，特别是外周血氧饱和度（SpO2）水平和并发合并症在很大程度上决定了他们需要入住 ICU，但一些实验室参数可能有助于评估疾病的严重程度。临床医生应考虑淋巴细胞计数低以及 CRP、D-二聚体、铁蛋白、肌钙蛋白和 IL-6 的血清水平，这些参数可用于风险分层，以预测住院患者的严重和致命 COVID-19。如果这些参数中的一些或全部发生改变，则疾病的进程更有可能不利。
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