Watanabe Kunihiko
The Home Hospice.
Gan To Kagaku Ryoho. 2020 May;47(5):797-800.
Cancer pain was observed in 131 of 160 patients with advanced cancer living at home. Oxycodone or morphine was administered to patients suffering from cancer pain or fentanyl transdermal patch was switched to morphine. Subsequently, 70 patients were found to have alleviation of symptoms such as nausea/vomiting, dyspnea, abdominal fullness, general fatigue, cough, and urinary urgency in addition to pain. Pain was defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage by the International Association for the Study of Pain. This definition of pain is cited in a lot of books. However, the author was unable to intervene with detailed reports of unpleasant sensations associated with tissue damage. Therefore, here the author reports about an unpleasant sensation caused by tissue damage of cancer that was alleviated by oxycodone or morphine.
在家居住的160例晚期癌症患者中,有131例出现癌痛。对癌痛患者给予羟考酮或吗啡治疗,或从芬太尼透皮贴剂转换为吗啡治疗。随后发现,70例患者除疼痛外,恶心/呕吐、呼吸困难、腹胀、全身乏力、咳嗽及尿急等症状也有所缓解。疼痛被定义为与实际的或潜在的组织损伤相关的一种令人不快的感觉和情绪体验,或按国际疼痛研究协会的说法是用这种损伤来描述的体验。许多书籍都引用了这个疼痛的定义。然而,作者无法对与组织损伤相关的不愉快感觉的详细报告进行干预。因此,在此作者报告了一种由癌症组织损伤引起的、经羟考酮或吗啡治疗后得以缓解的不愉快感觉。