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希腊的自闭症谱系障碍:10至11岁儿童的全国患病率及地区差异

Autism Spectrum Disorders in Greece: Nationwide Prevalence in 10-11 Year-Old Children and Regional Disparities.

作者信息

Thomaidis Loretta, Mavroeidi Nikoletta, Richardson Clive, Choleva Antigoni, Damianos George, Bolias Konstantinos, Tsolia Maria

机构信息

Developmental Assessment Unit, Second Department of Pediatrics "P. & A. Kyriakou" Children's Hospital, National and Kapodistrian University of Athens School of Medicine, 11527 Athens, Greece.

Panteion University of Social and Political Sciences, 17671 Athens, Greece.

出版信息

J Clin Med. 2020 Jul 8;9(7):2163. doi: 10.3390/jcm9072163.

Abstract

Autism spectrum disorders (ASD) constitute a public health concern with increasing prevalence worldwide. We aimed to estimate prevalence and age at diagnosis in Greece, where no large-scale prevalence study has ever been conducted. Aggregate data were collected on ASD diagnoses by gender and calendar year of diagnosis up to 2019, for children born in 2008 and 2009, from the Centers for Educational and Counseling Support, which evaluate children to receive special educational support in school. Coverage was 87.1% of centers and 88.1% of schoolchildren born in 2008-9. ASD prevalence overall was 1.15% (1.83% males, 0.44% females; ratio 4.14:1), ranging from 0.59% to 1.50% in Greece's 13 regions. In five regions, prevalence differed significantly between centers. Overall, only 3.8% of diagnoses were made before the fourth year after birth and 42.7% before the sixth year, with considerable variation between regions. Approximate mean age at diagnosis was six years and one month, and about three months earlier for girls than for boys. Our results provide evidence-based information to guide service planning and development at national and regional levels. Particular attention should be paid to smoothing out inequalities regarding service accessibility and provision. Emphasis should be given to earlier identification and diagnosis of ASD.

摘要

自闭症谱系障碍(ASD)是一个全球患病率不断上升的公共卫生问题。我们旨在估算希腊的患病率及诊断年龄,此前该国从未进行过大规模患病率研究。我们从教育与咨询支持中心收集了2008年和2009年出生儿童截至2019年按性别和诊断日历年划分的ASD诊断汇总数据,这些中心负责对儿童进行评估,以便其在学校获得特殊教育支持。覆盖范围为87.1%的中心以及2008 - 2009年出生学童的88.1%。总体ASD患病率为1.15%(男性为1.83%,女性为0.44%;比例为4.14:1),在希腊的13个地区中,患病率从0.59%到1.50%不等。在五个地区,各中心之间的患病率存在显著差异。总体而言,只有3.8%的诊断是在出生后第四年之前做出的,42.7%是在第六年之前做出的,各地区之间存在相当大的差异。诊断时的近似平均年龄为六岁零一个月,女孩比男孩早约三个月。我们的结果提供了基于证据的信息,以指导国家和地区层面的服务规划与发展。应特别注意消除服务可及性和提供方面的不平等现象。应重视ASD的早期识别和诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a132/7408756/5e3da894a795/jcm-09-02163-g001.jpg

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