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香叶醇的一百张面孔。

One Hundred Faces of Geraniol.

机构信息

Department of Chemistry, Wroclaw University of Environmental and Life Science, Norwida 25, 50-375 Wroclaw, Poland.

出版信息

Molecules. 2020 Jul 21;25(14):3303. doi: 10.3390/molecules25143303.

Abstract

Geraniol is a monoterpenic alcohol with a pleasant rose-like aroma, known as an important ingredient in many essential oils, and is used commercially as a fragrance compound in cosmetic and household products. However, geraniol has a number of biological activities, such as antioxidant and anti-inflammatory properties. In addition, numerous in vitro and in vivo studies have shown the activity of geraniol against prostate, bowel, liver, kidney and skin cancer. It can induce apoptosis and increase the expression of proapoptotic proteins. The synergy of this with other drugs may further increase the range of chemotherapeutic agents. The antibacterial activity of this compound was also observed on respiratory pathogens, skin and food-derived strains. This review discusses some of the most important uses of geraniol.

摘要

香叶醇是一种具有宜人玫瑰香气的单萜醇,是许多精油的重要成分,在商业上用作化妆品和家用产品中的香料化合物。然而,香叶醇具有多种生物活性,如抗氧化和抗炎特性。此外,许多体外和体内研究表明香叶醇对前列腺癌、肠癌、肝癌、肾癌和皮肤癌具有活性。它可以诱导细胞凋亡并增加促凋亡蛋白的表达。这种化合物与其他药物的协同作用可能会进一步增加化疗药物的范围。该化合物对呼吸道病原体、皮肤和食物来源的菌株也具有抗菌活性。本文讨论了香叶醇的一些最重要的用途。

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