Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Pain Med. 2020 Dec 25;21(12):3283-3291. doi: 10.1093/pm/pnaa233.
Enhanced recovery after surgery (ERAS) pathways have previously been shown to be feasible and safe in elective spinal procedures. As publications on ERAS pathways have recently emerged in elective neurosurgery, long-term outcomes are limited. We report on our 18-month experience with an ERAS pathway in elective spinal surgery.
A historical cohort of 149 consecutive patients was identified as the control group, and 1,141 patients were prospectively enrolled in an ERAS protocol. The primary outcome was the need for opioid use one month postoperation. Secondary outcomes were opioid and nonopioid consumption on postoperative day (POD) 1, opioid use at three and six months postoperation, inpatient pain scores, patient satisfaction scores, postoperative Foley catheter use, mobilization/ambulation on POD0-1, length of stay, complications, and intensive care unit admissions.
There was significant reduction in use of opioids at one, three, and six months postoperation (38.6% vs 70.5%, P < 0.001, 36.5% vs 70.9%, P < 0.001, and 23.6% vs 51.9%, P = 0.008) respectively. Both groups had similar surgical procedures and demographics. PCA use was nearly eliminated in the ERAS group (1.4% vs 61.6%, P < 0.001). ERAS patients mobilized faster on POD0 compared with control (63.5% vs 20.7%, P < 0.001). Fewer patients in the ERAS group required postoperative catheterization (40.7% vs 32.7%, P < 0.001). The ERAS group also had decreased length of stay (3.4 vs 3.9 days, P = 0.020).
ERAS protocols for all elective spine and peripheral nerve procedures are both possible and effective. This standardized approach to patient care decreases opioid usage, eliminates the use of PCAs, mobilizes patients faster, and reduces length of stay.
加速康复外科(ERAS)路径先前已被证明在择期脊柱手术中是可行且安全的。由于最近在择期神经外科中出现了关于 ERAS 路径的出版物,因此长期结果有限。我们报告了我们在择期脊柱手术中使用 ERAS 路径的 18 个月经验。
将 149 例连续患者确定为对照组,并前瞻性纳入 1141 例患者进行 ERAS 方案。主要结果是术后 1 个月需要使用阿片类药物。次要结果是术后第 1 天(POD)的阿片类药物和非阿片类药物消耗、术后 3 个月和 6 个月的阿片类药物使用、住院疼痛评分、患者满意度评分、术后 Foley 导管使用、POD0-1 时的动员/活动、住院时间、并发症和重症监护病房入院。
术后 1、3 和 6 个月阿片类药物的使用显著减少(38.6%对 70.5%,P<0.001,36.5%对 70.9%,P<0.001,和 23.6%对 51.9%,P=0.008)。两组的手术程序和人口统计学特征相似。ERAS 组中 PCA 的使用几乎消除(1.4%对 61.6%,P<0.001)。ERAS 患者在 POD0 时更快地移动,与对照组相比(63.5%对 20.7%,P<0.001)。ERAS 组术后需要导尿管的患者较少(40.7%对 32.7%,P<0.001)。ERAS 组的住院时间也较短(3.4 对 3.9 天,P=0.020)。
所有择期脊柱和周围神经手术的 ERAS 方案都是可行且有效的。这种标准化的患者护理方法减少了阿片类药物的使用,消除了 PCA 的使用,使患者更快地移动,并缩短了住院时间。