Mumtaz Hassan, Shafiq Muhammad Ahsan, Batool Hajra, Naz Tayyaba, Ambreen Saima
Internal Medicine, Rawalpindi Medical University, Rawalpindi, PAK.
Internal Medicine, Rawalpindi Medical University, Islamabad, PAK.
Cureus. 2020 Aug 27;12(8):e10065. doi: 10.7759/cureus.10065.
Diabetes is a common disease, and the number of patients is increasing every year. We report a case of a 34-year-old man with a history of diabetes mellitus (diagnosed at eight years old) and was on treatment with tablet glimepride with poor compliance. The patient sought consultation due to vomiting and abdominal pain 12 hours after onset along with burning micturition for four days. His initial blood sugar random (BSR) level was 84 mg/dL. Further lab tests revealed pH: 7.14, bicarbonate: 6.4 mEq/dL, sodium: 141, potasium: 3.8, chloride: 107, PO2: 115, PCO2: 19.4, serum amylase: 51, base excess (BE): -21.3 mmol/L, and positive ketonemia, i.e. 1.39. He was reanimated with parenteral crystalloids and insulin infusion. Eventually with subsequent arterial blood gases (ABGs) and ketones, the patient got better and was eventually declared to be out of diabetic ketoacidosis (DKA) and later discharged. There are very less studies done on euglycemic DKA (eu-DKA); so many physicians fail to diagnose the patients properly and they fall into the invisible cases chunk.
糖尿病是一种常见疾病,患者数量逐年增加。我们报告一例34岁男性病例,该患者有糖尿病病史(8岁时确诊),一直服用格列美脲片,但依从性差。患者在发病12小时后因呕吐、腹痛以及四天来的尿痛前来咨询。其初始随机血糖(BSR)水平为84mg/dL。进一步实验室检查显示:pH值7.14,碳酸氢根6.4mEq/dL,钠141,钾3.8,氯107,氧分压115,二氧化碳分压19.4,血清淀粉酶51,碱剩余(BE)-21.3mmol/L,酮血症阳性,即1.39。给予患者静脉输注晶体液和胰岛素进行复苏治疗。最终,随着后续动脉血气(ABG)和酮体检查结果好转,患者最终脱离糖尿病酮症酸中毒(DKA)状态并出院。关于正常血糖性DKA(eu-DKA)的研究非常少;因此许多医生无法正确诊断此类患者,这些患者就成为了易被忽视的病例。