定植抗力抵御艰难梭菌的机制。
Mechanisms of Colonization Resistance Against Clostridioides difficile.
机构信息
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
出版信息
J Infect Dis. 2021 Jun 16;223(12 Suppl 2):S194-S200. doi: 10.1093/infdis/jiaa408.
Abstract
Clostridioides difficile is an urgent antimicrobial-resistant bacterium, causing mild to moderate and sometimes life-threatening disease. Commensal gut microbes are critical for providing colonization resistance against C difficile and can be leveraged as non-antibiotic alternative therapeutics for the prevention and treatment of C difficile infection.
摘要
艰难梭菌是一种紧急的抗微生物药物耐药菌，可导致轻度至中度，有时甚至危及生命的疾病。共生肠道微生物对于提供针对艰难梭菌的定植抵抗至关重要，可作为预防和治疗艰难梭菌感染的非抗生素替代疗法加以利用。
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