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草药产品或制剂能否缓解成人的神经性疼痛?Cochrane 综述摘要及评论。

Can herbal medicinal products or preparations alleviate neuropathic pain in adults? A Cochrane Review summary with commentary.

机构信息

IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.

出版信息

NeuroRehabilitation. 2021;48(1):149-152. doi: 10.3233/NRE-209009.

Abstract

BACKGROUND

Several medicines have been shown to be effective in treating neuropathic pain, but they can have damaging side effects, therefore people are now trying herbal products to help relieve pain.

OBJECTIVE

The aim of the Cochrane Review was to evaluate whether herbal products/preparations have an analgesic effectiveness in neuropathic pain and whether any side effects are associated with their use.

METHODS

The population addressed were adults aged ≥18 years, suffering from chronic neuropathic pain. Studies that investigated the effects of herbal products/preparations for the relief of neuropathic pain compared to any or no interventions were included.

RESULTS

Included studies did not show that herbal products/preparations have reduced pain intensity of 30% or above and there was no observable reduction in the total pain score.

CONCLUSIONS

There is insufficient evidence to suggest that herbal products/preparations have any efficacy in any neuropathic pain conditions. The current evidence is of very low quality resulting in serious uncertainties about the estimates of effect observed.

摘要

背景

已有几种药物被证明可有效治疗神经性疼痛,但它们可能会产生有害的副作用,因此人们现在正在尝试使用草药产品来帮助缓解疼痛。

目的

本次 Cochrane 综述的目的是评估草药产品/制剂在神经性疼痛中的镇痛效果如何,以及使用它们是否会产生任何副作用。

方法

纳入研究的人群为年龄≥18 岁、患有慢性神经性疼痛的成年人。纳入的研究调查了与任何干预或不干预相比,草药产品/制剂在缓解神经性疼痛方面的效果。

结果

纳入的研究并未显示草药产品/制剂能将疼痛强度降低 30%或以上,且总疼痛评分也没有明显降低。

结论

没有足够的证据表明草药产品/制剂对任何神经性疼痛状况都具有疗效。目前的证据质量非常低,导致对观察到的疗效估计存在严重的不确定性。

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