Department of Surgery, Hospital "A. Rizzoli", Lacco Ameno, Naples, Italy.
Biomedical Research Institute (INCLIVA). Bioinformatics and Biostatistics Unit, Valencia, Spain.
Obes Surg. 2021 Apr;31(4):1722-1732. doi: 10.1007/s11695-020-05191-y. Epub 2021 Jan 4.
Considering the multitude of bariatric procedures performed all over the world, the necessity of revisional surgery increased accordingly. Several authors argued that with the great diffusion of sleeve gastrectomy (SG), the number of patients who experienced a weight regain at long follow-up was congruous and physiologic, even if not negligible. Recent studies showed that one anastomosis gastric bypass (OAGB) was an effective and safe option also as redo surgery. The aim of the study was to evaluate effectiveness of OAGB as redo surgery after SG in term of anthropometric features and remission of comorbidities.
Bariatric patients experiencing weight regain and insufficient weight loss after SG and undergoing OAGB as redo surgery were retrospectively analyzed. During post-OAGB outpatient visit weight, %EWL, BMI, comorbidities, and vitamin deficiencies were evaluated. A further visit was scheduled for the evaluation of postoperative esophagitis/gastritis at upper endoscopy.
Fifty-nine (Reviewer #3-1) patients underwent OAGB as redo-surgery consequently to the worsening of the bariatric outcomes at 29.42 ± 7.29 months from SG (mean weight, BMI and %EWL were 120.89 ± 16.79 kg, 43 ± 4.39 and 19.84 ± 30.29, respectively). Conversely, at a mean follow-up of 34.32 ± 1.71 months (Reviewer #3-3) after OAGB, no weight regain or insufficient weight loss cases were recorded (mean weight 71.25 ± 10.22 kg, mean BMI 24.46 ± 2.06 kg/m2, mean %EWL 69.49 ± 14.4, p < 0.0001) (Reviewer #3-2).
OAGB is a safe and effective bariatric procedure in terms of morbidity, mortality, and %EWL also as revision surgery after SG. Further larger studies are needed to address this issue.
考虑到全世界进行的众多减肥手术,翻修手术的必要性相应增加。一些作者认为,随着袖状胃切除术(SG)的广泛应用,在长期随访中经历体重反弹的患者数量是一致且合理的,尽管并非微不足道。最近的研究表明,单吻合口胃旁路术(OAGB)也是一种有效的、安全的选择,也可以作为翻修手术。本研究旨在评估 OAGB 作为 SG 后翻修手术在体重指标和并发症缓解方面的有效性。
回顾性分析了因 SG 后体重反弹和减重不足而接受 OAGB 作为翻修手术的减肥患者。在 OAGB 门诊随访期间,评估体重、%EWL、BMI、合并症和维生素缺乏情况。为了评估术后食管炎/胃炎,安排了进一步的上内窥镜检查。
59 例患者(Reviewer #3-1)在 SG 后 29.42±7.29 个月(平均体重、BMI 和 %EWL 分别为 120.89±16.79kg、43±4.39 和 19.84±30.29)时出现减肥效果恶化,行 OAGB 作为翻修手术。相反,在 OAGB 后的平均随访 34.32±1.71 个月(Reviewer #3-3)时,未记录到体重反弹或减重不足的病例(平均体重 71.25±10.22kg、平均 BMI 24.46±2.06kg/m2、平均 %EWL 69.49±14.4,p<0.0001)(Reviewer #3-2)。
OAGB 是一种安全有效的减肥手术,在发病率、死亡率和 %EWL 方面,以及作为 SG 后的翻修手术也是如此。需要进一步进行更大规模的研究来解决这个问题。