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基于纳米技术的骨科药物输送系统。

Nanotechnology-based drug delivery systems in orthopedics.

机构信息

Hacettepe Üniversitesi, Nanoteknoloji ve Nanotıp Anabilim Dalı, 06800 Beytepe, Ankara, Türkiye.

出版信息

Jt Dis Relat Surg. 2021;32(1):267-273. doi: 10.5606/ehc.2021.80360. Epub 2021 Jan 6.

Abstract

In recent years, nanotechnology has led to significant scientific and technological advances in diverse fields, specifically within the field of medicine. Owing to the revolutionary implications in drug delivery, nanotechnology-based drug delivery systems have gained an increasing research interest in the current medical field. A variety of nanomaterials with unique physical, chemical and biological properties have been engineered to develop new drug delivery systems for the local, sustained and targeted delivery of drugs with improved therapeutic efficiency and less or no toxicity, representing a very promising approach for the effective management of diseases. The utility of nanotechnology, particularly in the field of orthopedics, is a topic of extensive research. Nanotechnology has a great potential to revolutionize treatment, diagnostics, and research in the field of orthopedics. Nanophase drug delivery has shown great promise in their ability to deliver drugs at nanoscale for a variety of orthopedic applications. In this review, we discuss recent advances in the field of nanostructured drug delivery systems for orthopedic applications.

摘要

近年来,纳米技术在各个领域,特别是医学领域,取得了重大的科学和技术进步。由于在药物输送方面的革命性意义,基于纳米技术的药物输送系统在当前医学领域引起了越来越多的研究兴趣。各种具有独特物理、化学和生物特性的纳米材料被设计用于开发新的药物输送系统,以实现药物的局部、持续和靶向输送,提高治疗效果,减少或没有毒性,这是有效管理疾病的一种很有前途的方法。纳米技术的应用,特别是在骨科领域,是一个广泛研究的课题。纳米技术有可能彻底改变骨科领域的治疗、诊断和研究。纳米相药物输送在将药物递送至纳米级用于各种骨科应用方面显示出巨大的潜力。在这篇综述中,我们讨论了用于骨科应用的纳米结构药物输送系统的最新进展。

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