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关于罕见霉菌感染的诊断和管理,你需要了解的一切及更多信息。

All You Need to Know and More about the Diagnosis and Management of Rare Mold Infections.

机构信息

Section of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Medical University of Graz, Graz, Austria

Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, USA.

出版信息

mBio. 2021 Feb 23;12(1):e02920-20. doi: 10.1128/mBio.02920-20.

Abstract

Invasive mold infections caused by molds other than spp. or Mucorales are emerging. The reported prevalences of infection due to these rare fungal pathogens vary among geographic regions, driven by differences in climatic conditions, susceptible hosts, and diagnostic capabilities. These rare molds-, , and species and others-are difficult to detect and often show intrinsic antifungal resistance. Now, international societies of medical mycology and microbiology have joined forces and created the "Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology" (published in Lancet Infect Dis, https://doi.org/10.1016/S1473-3099(20)30784-2), with the goal of improving the diagnosis, treatment, prevention, and survival of persons with rare mold infections. The guideline provides cutting-edge guidance for the correct utilization and application of established and new diagnostic and therapeutic options.

摘要

由非 和毛霉目以外的霉菌引起的侵袭性霉菌感染正在出现。由于地理区域的气候条件、易感宿主和诊断能力的差异,这些罕见真菌病原体引起的感染的报告患病率有所不同。这些罕见的霉菌、 和 以及其他一些霉菌种类难以检测,且通常表现出固有抗真菌耐药性。现在,医学真菌学和微生物学的国际协会已经联合起来,制定了“罕见霉菌感染的诊断和管理全球指南:欧洲医学真菌学联合会与国际人类与动物真菌学学会以及美国微生物学会合作的倡议”(发表于《柳叶刀感染病学》,https://doi.org/10.1016/S1473-3099(20)30784-2),旨在改善罕见霉菌感染者的诊断、治疗、预防和生存。该指南为正确利用和应用既定和新的诊断和治疗选择提供了最新指导。

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