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COVID-19 大流行期间院外心脏骤停的数量和特征。

Out-of-hospital cardiac arrest volumes and characteristics during the COVID-19 pandemic.

机构信息

Department of Emergency Medicine, Indiana University, 1701 N Senate Ave, Indianapolis, IN 46202, United States.

Department of Emergency Medicine, Indiana University, 1701 N Senate Ave, Indianapolis, IN 46202, United States.

出版信息

Am J Emerg Med. 2021 Oct;48:191-197. doi: 10.1016/j.ajem.2021.04.072. Epub 2021 Apr 27.

Abstract

AIM

The COVID-19 pandemic has significantly impacted Emergency Medical Services (EMS) operations throughout the country. Some studies described variation in total volume of out-of-hospital cardiac arrests (OHCA) during the pandemic. We aimed to describe the changes in volume and characteristics of OHCA patients and resuscitations in one urban EMS system.

METHODS

We performed a retrospective cohort analysis of all recorded atraumatic OHCA in Marion County, Indiana, from January 1, 2019 to June 30, 2019 and from January 1, 2020 to June 30, 2020. We described patient, arrest, EMS response, and survival characteristics. We performed paired and unpaired t-tests to evaluate the changes in those characteristics during COVID-19 as compared to the prior year. Data were matched by month to control for seasonal variation.

RESULTS

The total number of arrests increased from 884 in 2019 to 1034 in 2020 (p = 0.016). Comparing 2019 to 2020, there was little difference in age [median 62 (IQR 59-73) and 60 (IQR 47-72), p = 0.086], gender (38.5% and 39.8% female, p = 0.7466, witness to arrest (44.3% and 39.6%, p = 0.092), bystander AED use (10.1% and 11.4% p = 0.379), bystander CPR (48.7% and 51.4%, p = 0.242). Patients with a shockable initial rhythm (19.2% and 15.4%, p = 0.044) both decreased in 2020, and response time increased by 18 s [6.0 min (IQR 4.5-7.7) and 6.3 min (IQR 4.7-8.0), p = 0.008]. 47.7% and 54.8% (p = 0.001) of OHCA patients died in the field, 19.7% and 19.3% (p = 0.809) died in the Emergency Department, 21.8% and 18.5% (p = 0.044) died in the hospital, 10.8% and 7.4% (p = 0.012) were discharged from the hospital, and 9.3% and 5.9% (p = 0.005) were discharged with Cerebral Performance Category score ≤ 2.

CONCLUSION

Total OHCA increased during the COVID-19 pandemic when compared with the prior year. Although patient characteristics were similar, initial shockable rhythm, and proportion of patients who died in the hospital decreased during the pandemic. Further investigation will explore etiologies of those findings.

摘要

目的

COVID-19 大流行对全国范围内的紧急医疗服务(EMS)运营产生了重大影响。一些研究描述了大流行期间院外心脏骤停(OHCA)总数量的变化。我们旨在描述一个城市 EMS 系统中 OHCA 患者和复苏数量和特征的变化。

方法

我们对印第安纳州马里恩县 2019 年 1 月 1 日至 2019 年 6 月 30 日和 2020 年 1 月 1 日至 2020 年 6 月 30 日期间记录的所有非创伤性 OHCA 进行了回顾性队列分析。我们描述了患者、骤停、EMS 反应和生存特征。我们进行了配对和非配对 t 检验,以评估 COVID-19 期间与前一年相比这些特征的变化。数据按月份匹配,以控制季节性变化。

结果

总逮捕人数从 2019 年的 884 人增加到 2020 年的 1034 人(p = 0.016)。与 2019 年相比,2020 年年龄[中位数 62(IQR 59-73)和 60(IQR 47-72),p = 0.086]、性别(38.5%和 39.8%女性,p = 0.7466,目击者到逮捕(44.3%和 39.6%,p = 0.092),旁观者除颤器使用(10.1%和 11.4%,p = 0.379),旁观者心肺复苏术(48.7%和 51.4%,p = 0.242)几乎没有差异。初始可电击节律的患者[19.2%和 15.4%,p = 0.044]均减少,反应时间增加 18 秒[6.0 分钟(IQR 4.5-7.7)和 6.3 分钟(IQR 4.7-8.0),p = 0.008]。54.8%(p = 0.001)的 OHCA 患者在现场死亡,19.7%(p = 0.001)在急诊室死亡,21.8%(p = 0.044)在医院死亡,10.8%(p = 0.012)出院,9.3%(p = 0.005)出院时格拉斯哥预后评分≤2 分。

结论

与前一年相比,COVID-19 大流行期间 OHCA 总数增加。尽管患者特征相似,但在大流行期间,初始可电击节律和在医院死亡的患者比例下降。进一步的研究将探讨这些发现的病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af79/8076765/d3235d8bf269/gr1_lrg.jpg

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