Hackler Eddie L, Hamburg Naomi M, White Solaru Khendi T
Division of Cardiovascular Medicine, Harrington Heart and Vascular Institute, University Hospitals, Cleveland, OH (E.L.H., K.W.S.).
Cardiology, Boston University School of Medicine, Medicine, MA (N.M.H.).
Circ Res. 2021 Jun 11;128(12):1913-1926. doi: 10.1161/CIRCRESAHA.121.318243. Epub 2021 Jun 10.
Peripheral artery disease is an obstructive, atherosclerotic disease of the lower extremities causing significant morbidity and mortality. Black Americans are disproportionately affected by this disease while they are also less likely to be diagnosed and promptly treated. The consequences of this disparity can be grim as Black Americans bear the burden of lower extremity amputation resulting from severe peripheral artery disease. The risk factors of peripheral artery disease and how they differentially affect certain groups are discussed in addition to a review of pharmacological and nonpharmacological treatment modalities. The purpose of this review is to highlight health care inequities and provide a review and resource of available recommendations for clinical management of all patients with peripheral artery disease.
外周动脉疾病是一种下肢阻塞性动脉粥样硬化疾病,会导致严重的发病率和死亡率。美国黑人受这种疾病的影响尤为严重,同时他们被诊断和及时治疗的可能性也较小。这种差异的后果可能很严峻,因为美国黑人承受着严重外周动脉疾病导致的下肢截肢负担。除了回顾药物和非药物治疗方式外,还讨论了外周动脉疾病的危险因素以及它们如何对特定群体产生不同影响。本综述的目的是突出医疗保健不平等问题,并为所有外周动脉疾病患者的临床管理提供现有建议的综述和资源。