18F-FDG、68Ga-FAPI 和 68Ga-DOTATATE PET/CT 在胰腺神经内分泌肿瘤患者中的比较。
Comparison of 18F-FDG, 68Ga-FAPI, and 68Ga-DOTATATE PET/CT in a Patient With Pancreatic Neuroendocrine Tumor.
机构信息
From the Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
出版信息
Clin Nucl Med. 2021 Sep 1;46(9):764-765. doi: 10.1097/RLU.0000000000003763.
We present image findings of 18F-FDG, 68Ga-FAPI, and 68Ga-DOTATATE PET/CT in a 35-year-old woman with multiple metastases of pancreatic neuroendocrine tumor. The images of PET/CTs using 3 different tracers all showed multiple foci of increased activities in the liver and pancreas body, in which 68Ga-FAPI PET/CT displayed the highest tumor-to-liver ratios. However, 68Ga-DOTATATE PET/CT detected more small metastatic lymph node and bone metastases, which were missed by both FDG and FAPI PET/CT.
我们呈现了一位 35 岁女性的 18F-FDG、68Ga-FAPI 和 68Ga-DOTATATE PET/CT 影像结果，该女性患有胰腺神经内分泌肿瘤的多处转移。使用 3 种不同示踪剂的 PET/CT 图像均显示肝脏和胰体部多个部位的活性增加，其中 68Ga-FAPI PET/CT 显示出最高的肿瘤与肝脏比值。然而，68Ga-DOTATATE PET/CT 检测到更多的小转移淋巴结和骨转移，这些在 FDG 和 FAPI PET/CT 中均被遗漏。
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