Social Determinants of Health Research Center, Department of Public Health, School of Health, Birjand University of Medical Science, Birjand, Iran.
Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Food Chem Toxicol. 2021 Aug;154:112349. doi: 10.1016/j.fct.2021.112349. Epub 2021 Jun 16.
In the present study, the concentration of (potentially toxic element) PTEs in the five fish species from the Caspian Sea (from five coastal areas) was measured and compared. The target hazard quotient (THQ) and total THQ (TTHQ) were calculated using Monte Carlo simulations to determine the non-carcinogenic risk in both children and adults consumers. The highest concentration of PTEs was associated with chromium (Cr) measured in Cyprinus carpio, sampled from Bandar Anzali (1.56 ± 0.14 μg/g dw), and the minimum PTEs level was nickel (Ni) in Vimba from Astara (0.02 ± 0.01 μg/g d w). The rank order for PTEs based on THQ was mercury (Hg) > cadmium (Cd) > lead (Pb)> Ni > tin (Sn) > Total Cr. For adults, the fishes rank order based on TTHQ was: Cyprinus carpio (3.268) > Chelon saliens (2.89) > Rutilus frisii kutum kanesky (2.28) > Oncorhynchus mykis (1.39) > Vimba (0.25); and for children was Cyprinus carpio (15.25) > Chelon saliens (13.47) > Rutilus frisii kutum kanesky (10.63) > Oncorhynchus mykis (6.48) > Vimba (1.16). Overall this study showed that the levels of PTEs in investigated fish species had a potential non-carcinogenic risk for both children and adults (TTHQ>1).
在本研究中,测量并比较了里海五种鱼类(来自五个沿海地区)中(潜在有毒元素)PTE 的浓度。使用蒙特卡罗模拟计算目标危害系数 (THQ) 和总危害系数 (TTHQ),以确定儿童和成人消费者的非致癌风险。Cr 在鲤鱼中的浓度最高,取自安扎利港(1.56 ± 0.14 μg/g dw),而在阿斯塔拉的 Vimba 中 Ni 的浓度最低(0.02 ± 0.01 μg/g dw)。基于 THQ 的 PTE 等级顺序为汞(Hg)>镉(Cd)>铅(Pb)>镍(Ni)>锡(Sn)>总铬。对于成年人,基于 TTHQ 的鱼类等级顺序为:鲤鱼(3.268)>海龟(2.89)>河鲈(2.28)>大鳞大麻哈鱼(1.39)> Vimba(0.25);对于儿童,顺序为鲤鱼(15.25)>海龟(13.47)>河鲈(10.63)>大鳞大麻哈鱼(6.48)> Vimba(1.16)。总体而言,本研究表明,在所研究的鱼类物种中,PTE 水平对儿童和成人都具有潜在的非致癌风险(TTHQ>1)。