Comparative Medicine, Interuniversity Messerli Research Institute, University of Veterinary Medicine and Medical University Vienna, Vienna, Austria.
Faculty of Science, Charles University, Prague, Czech Republic.
Allergy. 2022 Jan;77(1):55-71. doi: 10.1111/all.14991. Epub 2021 Jul 9.
The latest outbreak of a coronavirus disease in 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evolved into a worldwide pandemic with massive effects on health, quality of life, and economy. Given the short period of time since the outbreak, there are several knowledge gaps on the comparative and zoonotic aspects of this new virus. Within the One Health concept, the current EAACI position paper dwells into the current knowledge on SARS-CoV-2's receptors, symptoms, transmission routes for human and animals living in close vicinity to each other, usefulness of animal models to study this disease and management options to avoid intra- and interspecies transmission. Similar pandemics might appear unexpectedly and more frequently in the near future due to climate change, consumption of exotic foods and drinks, globe-trotter travel possibilities, the growing world population, the decreasing production space, declining room for wildlife and free-ranging animals, and the changed lifestyle including living very close to animals. Therefore, both the society and the health authorities need to be aware and well prepared for similar future situations, and research needs to focus on prevention and fast development of treatment options (medications, vaccines).
2019 年由严重急性呼吸系统综合症冠状病毒 2(SARS-CoV-2)引起的最新一轮冠状病毒疾病(COVID-19)爆发,演变成了一场全球性的大流行,对健康、生活质量和经济造成了巨大影响。鉴于此次疫情爆发时间较短,人们对这种新型病毒在比较和人畜共患方面的认识仍存在一些空白。在同一健康理念下,目前的 EAACI 立场文件深入探讨了 SARS-CoV-2 的受体、症状、密切接触的人类和动物的传播途径、动物模型在研究该疾病方面的用途以及避免种内和种间传播的管理选项。由于气候变化、食用异国食品和饮料、环球旅行的可能性、世界人口的不断增长、生产空间的减少、野生动物和自由放养动物的活动空间减少以及包括与动物近距离生活在内的生活方式的改变,类似的大流行可能会在不久的将来出人意料地更加频繁地出现。因此,社会和卫生当局都需要对此类未来情况保持警惕并做好充分准备,研究重点需要放在预防和快速开发治疗方法(药物、疫苗)上。