Pathobiology and Population Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, AL9 7TA, Herts, UK.
The Roslin Institute and the Royal (Dick), School of Veterinary Studies, The University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.
Sci Rep. 2021 Jul 14;11(1):13988. doi: 10.1038/s41598-021-93379-2.
The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study aimed to explore the relative risk to common disorders in the Labrador Retriever. The clinical records of a random sample of dogs were reviewed to extract the most definitive diagnoses for all disorders recorded during 2016. A list of disorders was generated, including the 30 most common disorders in Labrador Retrievers and the 30 most common disorders in non-Labrador Retrievers. Multivariable logistic regression was used to report the odds of each of these disorders in 1462 (6.6%) Labrador Retrievers compared with 20,786 (93.4%) non-Labrador Retrievers. At a specific-level of diagnostic precision, after accounting for confounding, Labrador Retrievers had significantly increased odds of 12/35 (34.3%) disorders compared to non-Labrador Retrievers; osteoarthritis (OR 2.83) had the highest odds. Conversely, Labrador Retrievers had reduced odds of 7/35 (20.0%) disorders; patellar luxation (OR 0.18) had the lowest odds. This study provides useful information about breed-specific disorder predispositions and protections, which future research could evaluate further to produce definitive guidance for Labrador Retriever breeders and owners.
拉布拉多猎犬是全球最受欢迎的犬种之一,因此了解该品种的常见健康问题的可靠证据非常重要。本研究使用 VetCompass 计划的匿名兽医临床数据,旨在探讨拉布拉多猎犬常见疾病的相对风险。对随机抽取的犬只的临床记录进行了回顾,以提取 2016 年记录的所有疾病的最明确诊断。生成了一份疾病清单,包括拉布拉多猎犬中最常见的 30 种疾病和非拉布拉多猎犬中最常见的 30 种疾病。多变量逻辑回归用于报告 1462 只(6.6%)拉布拉多猎犬与 20786 只(93.4%)非拉布拉多猎犬相比,这些疾病中的每一种的患病几率。在特定的诊断精度水平下,在考虑混杂因素后,拉布拉多猎犬与非拉布拉多猎犬相比,有 12/35(34.3%)疾病的患病几率显著增加;骨关节炎(OR 2.83)的患病几率最高。相反,拉布拉多猎犬有 7/35(20.0%)疾病的患病几率降低;髌骨脱位(OR 0.18)的患病几率最低。本研究提供了有关品种特异性疾病易感性和保护的有用信息,未来的研究可以进一步评估这些信息,为拉布拉多猎犬饲养者和所有者提供明确的指导。