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人乳头瘤病毒疫苗接种的社会人口学关联因素:挪威的机会性接种和补种

Sociodemographic Correlates of Human Papillomavirus Vaccine Uptake: Opportunistic and Catch-Up Vaccination in Norway.

作者信息

Dong Li, Nygård Mari, Hansen Bo T

机构信息

Department of Research, Cancer Registry of Norway, 0304 Oslo, Norway.

Institutes of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.

出版信息

Cancers (Basel). 2021 Jul 12;13(14):3483. doi: 10.3390/cancers13143483.

Abstract

Achieving equity in human papillomavirus (HPV) vaccination has high priority. In this nationwide registry-based study, we aimed to investigate sociodemographic correlates of HPV vaccine uptake among women who were vaccinated opportunistically at their own initiative and cost during October 2006-June 2018, and among women who were vaccinated free-of-charge in a catch-up vaccination program during November 2016-June 2018. For 840,328 female residents born in Norway between 1975 and 1996, we retrieved HPV vaccination and sociodemographic data from national registries. We used separate models to analyze the sociodemographic correlates of the initiation and completion of HPV vaccination in opportunistic and catch-up vaccination settings. Overall initiation rate for opportunistic HPV vaccination was 2.2%. Uptake increased consistently with birth year, maternal education level, and household income. Having two immigrant parents or a mother working in a lower prestige occupation was strongly associated with low opportunistic vaccination uptake. Similar but weaker inequities were observed in catch-up HPV vaccination. Initiation rate during the first 20 months of the catch-up program was 46.2%. Completion rate was 72.1% and 73.0% for opportunistic or catch-up vaccination, respectively, with small inequities. In conclusion, HPV vaccine uptake was strongly associated with sociodemographic background both in opportunistic and catch-up vaccination settings, with particularly low uptake associated with having two immigrant parents and low household income.

摘要

实现人乳头瘤病毒(HPV)疫苗接种的公平性是当务之急。在这项基于全国登记系统的研究中,我们旨在调查2006年10月至2018年6月期间自行自费进行机会性接种HPV疫苗的女性,以及2016年11月至2018年6月期间在补种疫苗计划中免费接种HPV疫苗的女性的社会人口学相关因素。对于840328名1975年至1996年出生在挪威的女性居民,我们从国家登记系统中获取了HPV疫苗接种和社会人口学数据。我们使用不同的模型来分析机会性接种和补种疫苗情况下HPV疫苗接种起始和完成的社会人口学相关因素。机会性HPV疫苗接种的总体起始率为2.2%。接种率随出生年份、母亲教育水平和家庭收入持续上升。父母双方均为移民或母亲从事声望较低职业的女性,其机会性疫苗接种率较低。在补种HPV疫苗中也观察到了类似但较弱的不平等现象。补种计划前20个月的起始率为46.2%。机会性接种或补种疫苗的完成率分别为72.1%和73.0%,不平等现象较小。总之,在机会性接种和补种疫苗情况下,HPV疫苗接种与社会人口学背景密切相关,父母双方均为移民且家庭收入较低的人群接种率尤其低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1d/8307029/f59fc30afa36/cancers-13-03483-g001.jpg

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