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产碳青霉烯酶肠杆菌科细菌暴发的检测与快速管理建议。

Recommendations for detection and rapid management of carbapenemase-producing Enterobacterales outbreaks.

作者信息

Puleston R, Brown C S, Patel B, Fry C, Singleton S, Robotham J V, Freeman R

机构信息

Field Service East Midlands, National Infection Service, Public Health England, Nottingham, UK.

Healthcare Associated Infections and Antimicrobial Resistance Division, National Infection Service, Public Health England, 61 Colindale Avenue, London, UK.

出版信息

Infect Prev Pract. 2020 Sep 1;2(3):100086. doi: 10.1016/j.infpip.2020.100086. eCollection 2020 Sep.

Abstract

There is large heterogeneity in approaches to tackling nosocomial outbreaks caused by carbapenemase-producing Enterobacterales (CPE), however there is limited guidance on how to approach their management. Rapid and robust infection prevention and control interventions can be effective in preventing and reducing the impact of outbreaks in healthcare environments. We present a stepwise approach to aspects of CPE outbreak management, including the development of an action plan, engagement and communication with key stakeholders, developing a dynamic risk assessment, and staff education. These can provide a blueprint for organisations to create templates and checklists to inform their own outbreak response.

摘要

在应对由产碳青霉烯酶肠杆菌科细菌(CPE)引起的医院感染暴发方面,方法存在很大差异,然而在如何进行管理方面的指导却很有限。快速且有力的感染预防与控制干预措施对于预防和减少医疗环境中感染暴发的影响可能是有效的。我们提出了一种针对CPE感染暴发管理各方面的逐步方法,包括制定行动计划、与关键利益相关者进行接触和沟通、开展动态风险评估以及对工作人员进行教育。这些可为各组织创建模板和清单以指导其自身的感染暴发应对提供蓝本。

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