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采用前路腰大肌技术行腰椎和腰骶融合术后假关节形成。

Pseudarthrosis Following Lumbar and Lumbosacral Fusion Using the Antepsoas Technique.

机构信息

Department of Orthopaedic Surgery, Boston Medical Center, Boston, MA.

出版信息

Spine (Phila Pa 1976). 2021 Dec 15;46(24):1690-1695. doi: 10.1097/BRS.0000000000004115.

Abstract

STUDY DESIGN

Retrospective case-control study.

OBJECTIVE

The aim of this study was to evaluate the prevalence of pseudarthrosis following antepsoas (ATP) lumbar and lumbosacral fusions.

SUMMARY OF BACKGROUND DATA

Pseudarthrosis is a feared complication following spinal fusions and may affect their clinical outcomes. To date there are no sufficient data on the fusion rate following ATP lumbar and lumbosacral arthrodesis.

METHODS

This is a retrospective review of 220 patients who underwent lumbar minimally invasive antepsoas (MIS-ATP) fusions between January 2008 and February 2019 who have at least 1-year postoperative computed tomography (CT) follow-up scans. Fusion was graded using CT scans imaging and adopting a 1-4 grading scale (1, definitely fused; 2, likely fused; 3, likely not fused; 4, definitely not fused/nonunion). Grades 3 or 4 indicate pseudarthrosis.

RESULTS

A total of 220 patients (average age: 66 years, 82 males (37.2%), and 127 (57.7%) smokers) were included. Eight patients (3.6%) developed pseudarthrosis. A total of 693 discs were addressed using the ATP approach. Of those, 681 (98.3%) were considered fused (641 levels [92.5%] were "definitely fused" and 40 levels [5.8%] were "Likely fused") and 12 discs (1.7%) developed pseudarthrosis (seven levels [1.0%] were "likely not fused" and five levels (0.7%) were "definitely not fused"). The highest rate of pseudarthrosis was found at L5-S1 (4.8%) compared to the L1-L5 discs (0-2%). Of 127 smokers, six developed pseudarthrosis (odds ratio = 2.3, P = 0.3). The fusion rates were 95.3% and 97.8% for smokers and nonsmokers, respectively. Of the eight patients who developed pseudarthrosis, only four (50%) were symptomatic, of whom two (25%) required revision surgery. Both of these patients were smokers. The overall revision rate due to pseudarthrosis was 0.9% (two of 220 patients).

CONCLUSION

The MIS-ATP technique results in a high fusion rate (96.4% of patients; 98.3% of levels). Pseudarthrosis was noted mostly at the L5-S1 discs and in smokers.Level of Evidence: 4.

摘要

研究设计

回顾性病例对照研究。

目的

本研究旨在评估前路(ATP)腰椎和腰骶融合术后假关节形成的发生率。

背景资料概要

假关节形成是脊柱融合术后一种可怕的并发症,可能影响其临床结果。迄今为止,尚无关于 ATP 腰椎和腰骶关节融合术后融合率的充分数据。

方法

这是一项对 2008 年 1 月至 2019 年 2 月期间接受腰椎微创前路(MIS-ATP)融合术的 220 例患者的回顾性研究,这些患者至少有 1 年的术后计算机断层(CT)随访扫描。融合程度采用 CT 扫描图像,并采用 1-4 级评分(1,完全融合;2,可能融合;3,可能不融合;4,肯定不融合/假关节)进行分级。3 级或 4 级表示假关节形成。

结果

共纳入 220 例患者(平均年龄:66 岁,82 例男性(37.2%),127 例(57.7%)吸烟者)。8 例(3.6%)发生假关节形成。共采用 ATP 方法处理 693 个椎间盘。其中,681 个(98.3%)被认为融合(641 个节段[92.5%]为“完全融合”,40 个节段[5.8%]为“可能融合”),12 个椎间盘(1.7%)发生假关节形成(7 个节段[1.0%]为“可能不融合”,5 个节段[0.7%]为“肯定不融合”)。假关节形成发生率最高的部位为 L5-S1(4.8%),而 L1-L5 椎间盘(0-2%)发生率较低。127 名吸烟者中,6 人发生假关节形成(比值比=2.3,P=0.3)。吸烟者的融合率为 95.3%,非吸烟者为 97.8%。发生假关节形成的 8 例患者中,仅有 4 例(50%)有症状,其中 2 例(25%)需要接受翻修手术。这两名患者均为吸烟者。因假关节形成而需要翻修的总发生率为 0.9%(220 例患者中有 2 例)。

结论

MIS-ATP 技术可获得较高的融合率(96.4%的患者;98.3%的节段)。假关节形成主要发生在 L5-S1 椎间盘和吸烟者中。

证据等级

4。

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