Department of Orthopaedic Surgery, Boston Medical Center, Boston, MA.
Spine (Phila Pa 1976). 2021 Dec 15;46(24):1690-1695. doi: 10.1097/BRS.0000000000004115.
Retrospective case-control study.
The aim of this study was to evaluate the prevalence of pseudarthrosis following antepsoas (ATP) lumbar and lumbosacral fusions.
Pseudarthrosis is a feared complication following spinal fusions and may affect their clinical outcomes. To date there are no sufficient data on the fusion rate following ATP lumbar and lumbosacral arthrodesis.
This is a retrospective review of 220 patients who underwent lumbar minimally invasive antepsoas (MIS-ATP) fusions between January 2008 and February 2019 who have at least 1-year postoperative computed tomography (CT) follow-up scans. Fusion was graded using CT scans imaging and adopting a 1-4 grading scale (1, definitely fused; 2, likely fused; 3, likely not fused; 4, definitely not fused/nonunion). Grades 3 or 4 indicate pseudarthrosis.
A total of 220 patients (average age: 66 years, 82 males (37.2%), and 127 (57.7%) smokers) were included. Eight patients (3.6%) developed pseudarthrosis. A total of 693 discs were addressed using the ATP approach. Of those, 681 (98.3%) were considered fused (641 levels [92.5%] were "definitely fused" and 40 levels [5.8%] were "Likely fused") and 12 discs (1.7%) developed pseudarthrosis (seven levels [1.0%] were "likely not fused" and five levels (0.7%) were "definitely not fused"). The highest rate of pseudarthrosis was found at L5-S1 (4.8%) compared to the L1-L5 discs (0-2%). Of 127 smokers, six developed pseudarthrosis (odds ratio = 2.3, P = 0.3). The fusion rates were 95.3% and 97.8% for smokers and nonsmokers, respectively. Of the eight patients who developed pseudarthrosis, only four (50%) were symptomatic, of whom two (25%) required revision surgery. Both of these patients were smokers. The overall revision rate due to pseudarthrosis was 0.9% (two of 220 patients).
The MIS-ATP technique results in a high fusion rate (96.4% of patients; 98.3% of levels). Pseudarthrosis was noted mostly at the L5-S1 discs and in smokers.Level of Evidence: 4.
回顾性病例对照研究。
本研究旨在评估前路(ATP)腰椎和腰骶融合术后假关节形成的发生率。
假关节形成是脊柱融合术后一种可怕的并发症,可能影响其临床结果。迄今为止,尚无关于 ATP 腰椎和腰骶关节融合术后融合率的充分数据。
这是一项对 2008 年 1 月至 2019 年 2 月期间接受腰椎微创前路(MIS-ATP)融合术的 220 例患者的回顾性研究,这些患者至少有 1 年的术后计算机断层(CT)随访扫描。融合程度采用 CT 扫描图像,并采用 1-4 级评分(1,完全融合;2,可能融合;3,可能不融合;4,肯定不融合/假关节)进行分级。3 级或 4 级表示假关节形成。
共纳入 220 例患者(平均年龄:66 岁,82 例男性(37.2%),127 例(57.7%)吸烟者)。8 例(3.6%)发生假关节形成。共采用 ATP 方法处理 693 个椎间盘。其中,681 个(98.3%)被认为融合(641 个节段[92.5%]为“完全融合”,40 个节段[5.8%]为“可能融合”),12 个椎间盘(1.7%)发生假关节形成(7 个节段[1.0%]为“可能不融合”,5 个节段[0.7%]为“肯定不融合”)。假关节形成发生率最高的部位为 L5-S1(4.8%),而 L1-L5 椎间盘(0-2%)发生率较低。127 名吸烟者中,6 人发生假关节形成(比值比=2.3,P=0.3)。吸烟者的融合率为 95.3%,非吸烟者为 97.8%。发生假关节形成的 8 例患者中,仅有 4 例(50%)有症状,其中 2 例(25%)需要接受翻修手术。这两名患者均为吸烟者。因假关节形成而需要翻修的总发生率为 0.9%(220 例患者中有 2 例)。
MIS-ATP 技术可获得较高的融合率(96.4%的患者;98.3%的节段)。假关节形成主要发生在 L5-S1 椎间盘和吸烟者中。
4。