Ullah Khan Atta, Chen Lan, Ge Guanglu
CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, No. 11 Zhongguancun Beiyitiao, Beijing 100190, China.
Inorg Chem Commun. 2021 Dec;134:108995. doi: 10.1016/j.inoche.2021.108995. Epub 2021 Oct 8.
In recent decades, the use of engineered nanoparticles has been increasing in various sectors, including biomedicine, diagnosis, water treatment, and environmental remediation leading to significant public concerns. Among these nanoparticles, magnetic nanoparticles (MNPs) have gained many attentions in medicine, pharmacology, drug delivery system, molecular imaging, and bio-sensing due to their various properties. In addition, various studies have reviewed MNPs main applications in the biomedical engineering area with intense progress and recent achievements. Nanoparticles, especially the magnetic nanoparticles, have recently been confirmed with excellent antiviral activity against different viruses, including SARS-CoV-2(Covid-19) and their recent development against Covid-19 also has also been discussed. This review aims to highlight the recent development of the magnetic nanoparticles and their biomedical applications such as diagnosis of diseases, molecular imaging, hyperthermia, bio-sensing, gene therapy, drug delivery and the diagnosis of Covid-19.
近几十年来,工程纳米粒子在包括生物医学、诊断、水处理和环境修复在内的各个领域的使用不断增加,引发了公众的重大关注。在这些纳米粒子中,磁性纳米粒子(MNPs)因其各种特性而在医学、药理学、药物递送系统、分子成像和生物传感等领域受到了广泛关注。此外,各种研究综述了磁性纳米粒子在生物医学工程领域的主要应用及其取得的显著进展和最新成果。纳米粒子,尤其是磁性纳米粒子,最近已被证实对包括SARS-CoV-2(新冠病毒)在内的不同病毒具有出色的抗病毒活性,并且还讨论了它们针对新冠病毒的最新进展。本综述旨在突出磁性纳米粒子的最新进展及其生物医学应用,如疾病诊断、分子成像、热疗、生物传感、基因治疗、药物递送以及新冠病毒的诊断。