Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Viruses. 2021 Oct 7;13(10):2019. doi: 10.3390/v13102019.
Solid organ transplant recipients are at increased risk for infections due to chronic immunosuppression. Diarrhea is a commonly encountered problem post transplantation, with infectious causes of diarrhea being a frequent complication. Viral infections/enteritides in solid organ transplant recipients often result from frequently encountered pathogens in this population such as cytomegalovirus, adenovirus, and norovirus. However, several emerging viral pathogens are increasingly being recognized as more sensitive diagnostic techniques become available. Treatment is often limited to supportive care and reduction in immunosuppression, though antiviral therapies mayplay a role in the treatment in certain diseases. Viral enteritis is an important entity that contributes to morbidity and mortality in transplant recipients.
实体器官移植受者由于慢性免疫抑制而面临更高的感染风险。腹泻是移植后常见的问题,感染性腹泻是常见的并发症。实体器官移植受者的病毒感染/肠炎通常是由该人群中常见的病原体引起的,如巨细胞病毒、腺病毒和诺如病毒。然而,随着更敏感的诊断技术的出现,一些新出现的病毒病原体越来越被认为是更为敏感的诊断技术。治疗通常限于支持性护理和减少免疫抑制,尽管抗病毒治疗在某些疾病中可能发挥作用。病毒性肠炎是导致移植受者发病率和死亡率的重要因素。