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急性新冠病毒感染性小脑炎:新冠病毒感染的一种罕见神经表现

Acute COVID-19 Cerebellitis: A Rare Neurological Manifestation of COVID-19 Infection.

作者信息

Malayala Srikrishna V, Jaidev Praveena, Vanaparthy Rachana, Jolly Taranjeet S

机构信息

Internal Medicine, Temple University Hospital, Philadelphia, USA.

Internal Medicine, University of Wisconsin, Madison, USA.

出版信息

Cureus. 2021 Oct 5;13(10):e18505. doi: 10.7759/cureus.18505. eCollection 2021 Oct.

Abstract

The COVID-19 virus is well known to cause respiratory tract infections but several non-respiratory presentations and post-infectious complications have been well reported since its origin. With this case report, we present a rare manifestation of COVID-19 infection that presented as acute cerebellitis. This is a case of a 63-year-old Caucasian male patient who presented with altered mental status and ataxia. He was diagnosed with COVID-19 infection about five days prior to presenting to the hospital. Neurological exam was consistent with cerebellar symptoms like broad bases gait, truncal ataxia and subsequent imaging revealed white matter degeneration and edema of the cerebellar hemispheres. The symptoms completely resolved following treatment of ongoing COVID-19 infection with corticosteroids and intravenous remdesivir. With this case report, we intend to discuss the available literature regarding the clinical manifestations, management, and prognosis of COVID-19-induced cerebellitis.

摘要

众所周知,新冠病毒会引发呼吸道感染,但自其出现以来,已有多项关于非呼吸道症状及感染后并发症的报道。通过本病例报告,我们呈现了新冠病毒感染的一种罕见表现形式,即急性小脑炎。这是一名63岁的白人男性患者,表现为精神状态改变和共济失调。他在入院前约五天被诊断为新冠病毒感染。神经系统检查结果与小脑症状相符,如宽基底步态、躯干共济失调,随后的影像学检查显示小脑半球白质变性和水肿。在用皮质类固醇和静脉注射瑞德西韦治疗新冠病毒持续感染后,症状完全缓解。通过本病例报告,我们旨在讨论有关新冠病毒诱发小脑炎的临床表现、治疗及预后的现有文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cbd/8569692/39f5ccfdb085/cureus-0013-00000018505-i01.jpg

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