Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
J Exp Med. 2021 Dec 6;218(12). doi: 10.1084/jem.20211665. Epub 2021 Nov 15.
The majority of humans infected with Mycobacterium tuberculosis never experience clinical symptoms or signs, but predicting those who will remains out of reach. Here, we discuss recent studies that reveal patterns and pathways that determine who is at highest risk for progression.
大多数感染结核分枝杆菌的人从未出现临床症状或体征,但预测谁会出现这些症状仍难以实现。在这里,我们讨论了最近的研究揭示的决定谁处于进展风险最高的模式和途径。