University of South Carolina, Columbia, South Carolina, USA.
Emory University School of Medicine, Atlanta, Georgia, USA.
Child Dev. 2021 Nov;92(6):2224-2234. doi: 10.1111/cdev.13683.
Social-communication differences are a robust and defining feature of autism spectrum disorder (ASD) but identifying early points of divergence in infancy has been a challenge. The current study examines social communication in 9- to 12-month-old infants who develop ASD (N = 30; 23% female; 70% white) compared to typically developing (TD) infants (N = 94, 38% female; 88% white). Results demonstrate that infants later diagnosed with ASD were already exhibiting fewer social-communication skills using eye gaze, facial expression, gestures, and sounds at 9 months (effect size: 0.42-0.89). Moreover, three unique patterns of change across distinct social-communication skills were observed within the ASD group. This study documents that observable social-communication differences for infants with ASD are unfolding by 9 months, pointing to a critical window for targeted intervention.
社交沟通差异是自闭症谱系障碍(ASD)的一个显著特征,但在婴儿期早期识别差异一直是一个挑战。本研究比较了 9 至 12 个月大的自闭症婴儿(N=30;23%女性;70%白人)和正常发育(TD)婴儿(N=94;38%女性;88%白人)的社交沟通。结果表明,在 9 个月大时,后来被诊断为自闭症的婴儿在用眼神、面部表情、手势和声音进行社交沟通时表现出较少的技能(效应量为 0.42-0.89)。此外,在 ASD 组中观察到三种独特的社交沟通技能变化模式。本研究记录了 ASD 婴儿的可观察社交沟通差异在 9 个月时就已经显现出来,这表明这是进行有针对性干预的关键窗口期。