Biomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, c/Guillem de Castro 94, 46001 Valencia, Valencia, Spain.
Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
ACS Appl Mater Interfaces. 2021 Dec 8;13(48):56725-56751. doi: 10.1021/acsami.1c12227. Epub 2021 Nov 19.
Management of the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has relied in part on the use of personal protective equipment (PPE). Face masks, as a representative example of PPE, have made a particularly significant contribution. However, most commonly used face masks are made of materials lacking inactivation properties against either SARS-CoV-2 or multidrug-resistant bacteria. Therefore, symptomatic and asymptomatic individuals wearing masks can still infect others due to viable microbial loads escaping from the masks. Moreover, microbial contact transmission can occur by touching the mask, and the discarded masks are an increasing source of contaminated biological waste and a serious environmental threat. For this reason, during the current pandemic, many researchers have worked to develop face masks made of advanced materials with intrinsic antimicrobial, self-cleaning, reusable, and/or biodegradable properties, thereby providing extra protection against pathogens in a sustainable manner. To overview this segment of the remarkable efforts against COVID-19, this review describes the different types of commercialized face masks, their main fabrication methods and treatments, and the progress achieved in face mask development.
严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2)引发的 COVID-19 大流行的管理部分依赖于个人防护设备 (PPE) 的使用。口罩作为 PPE 的一个代表性例子,做出了特别重大的贡献。然而,大多数常用的口罩由缺乏对 SARS-CoV-2 或多药耐药菌灭活特性的材料制成。因此,由于从口罩中逸出的有活力的微生物负荷,戴口罩的有症状和无症状个体仍可能感染他人。此外,通过触摸口罩可能发生微生物接触传播,而丢弃的口罩是受污染的生物废物不断增加的来源,也是对环境的严重威胁。出于这个原因,在当前大流行期间,许多研究人员致力于开发具有内在抗菌、自清洁、可重复使用和/或可生物降解特性的先进材料制成的口罩,从而以可持续的方式提供针对病原体的额外保护。为了概述这一对抗 COVID-19 的显著努力的一部分,本综述描述了商业化口罩的不同类型、它们的主要制造方法和处理方法,以及在口罩开发方面取得的进展。