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心血管疾病负担归因于 1990 年至 2019 年的饮食风险因素:全球疾病负担研究的系统分析。

Cardiovascular disease burden attributable to dietary risk factors from 1990 to 2019: A systematic analysis of the Global Burden of Disease study.

机构信息

Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.

出版信息

Nutr Metab Cardiovasc Dis. 2022 Apr;32(4):897-907. doi: 10.1016/j.numecd.2021.11.012. Epub 2021 Nov 29.

Abstract

BACKGROUND AND AIMS

Dietary risks have always been a major risk factor for cardiovascular diseases (CVDs), especially in young people. This article aimed to provide an updated and comprehensive view of the spatial, temporal and sexual heterogeneity in diet-attributable CVD burdens from 1990 to 2019.

METHODS AND RESULTS

Data on diet-attributable CVD burdens were extracted from the Global Burden of Disease (GBD) Study 2019. Numbers and age-standardized rates (ASRs) of deaths, disability-adjusted life years (DALYs) and corresponding estimated annual percentage change (EAPC) were determined. Globally, the number of diet-attributable CVD deaths and DALYs in 2019 were 6.9 million and 153.2 million, marking 43.8% and 34.3% increases since 1990, respectively. However, ASRs of death and DALYs have declined over time. The regions with the highest ASRs of diet-related CVD deaths and DALYs were in Central Asia, whereas the lowest ASRs of CVD deaths and DALYs were observed in the high-income Asia Pacific region. Globally, men suffered higher death and DALY burdens than women. Ischemic heart disease and stroke were the leading causes of CVD deaths and DALYs, globally. Regarding the specific diet group, diets low in whole grains, high in sodium, low in fruits, low in nuts and seeds, low in vegetables and low in seafood omega-3 fatty acids contributed to CVD deaths and DALYs the most. Dietary risks accounted for a higher proportion in people aged less than 65 years old.

CONCLUSIONS

Diet-attributable CVDs threaten public health, particularly in low SDI countries and younger generations. As diet-related CVDs are nation-specific, the prioritization of public health interventions should be evidence-based.

摘要

背景与目的

饮食风险一直是心血管疾病(CVDs)的主要危险因素,尤其是在年轻人中。本文旨在提供一个关于 1990 年至 2019 年饮食相关 CVD 负担的空间、时间和性别异质性的最新和全面的观点。

方法和结果

从 2019 年全球疾病负担研究中提取了与饮食相关的 CVD 负担的数据。确定了死亡人数、残疾调整生命年(DALYs)及其相应的估计年百分比变化(EAPC)。全球范围内,2019 年饮食相关 CVD 死亡人数和 DALYs 分别为 690 万和 1.532 亿,分别比 1990 年增加了 43.8%和 34.3%。然而,死亡和 DALY 的 ASR 呈下降趋势。饮食相关 CVD 死亡和 DALY 发生率最高的地区是中亚,而 CVD 死亡和 DALY 发生率最低的地区是高收入亚太地区。全球范围内,男性的死亡和 DALY 负担高于女性。缺血性心脏病和中风是全球 CVD 死亡和 DALY 的主要原因。就特定的饮食组而言,全谷物摄入不足、钠摄入过多、水果摄入不足、坚果和种子摄入不足、蔬菜摄入不足以及海鲜ω-3 脂肪酸摄入不足与 CVD 死亡和 DALY 关系最密切。饮食风险在年龄小于 65 岁的人群中占比更高。

结论

饮食相关的 CVD 对公共健康构成威胁,尤其是在低 SDI 国家和年轻一代中。由于与饮食相关的 CVD 具有国家特异性,公共卫生干预措施的优先顺序应基于证据。

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