辅助性T细胞谱系定向中的多胺代谢能否成为过敏研究的新靶点？ - Suppr

Can polyamine metabolism in T helper cell lineage commitment be a new target in allergy research?

作者信息

Huang Mengting, Rodriguez-Coira Juan

机构信息

Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland.

Instituto de Medicina Molecular Aplicada, Grupo Hospital Madrid, Universidad San Pablo-CEU, CEU Universities, Madrid, España.

出版信息

Allergy. 2022 Jun;77(6):1929-1930. doi: 10.1111/all.15265. Epub 2022 Mar 2.

DOI:10.1111/all.15265

PMID:35191039

Abstract

摘要

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Can polyamine metabolism in T helper cell lineage commitment be a new target in allergy research?

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Can polyamine metabolism in T helper cell lineage commitment be a new target in allergy research?

Allergy. 2022 Jun;77(6):1929-1930. doi: 10.1111/all.15265. Epub 2022 Mar 2.

Polyamine metabolism is a central determinant of helper T cell lineage fidelity.

Cell. 2021 Aug 5;184(16):4186-4202.e20. doi: 10.1016/j.cell.2021.06.007. Epub 2021 Jul 2.

Polyamine: A metabolic compass for T helper cell fate direction.

Cell. 2021 Aug 5;184(16):4109-4112. doi: 10.1016/j.cell.2021.07.012.

Shaping a helper T cell identity.

Nat Immunol. 2007 Feb;8(2):119-20. doi: 10.1038/ni0207-119.

T Helper Cell Lineage-Defining Transcription Factors: Potent Targets for Specific GVHD Therapy?

Front Immunol. 2022 Jan 5;12:806529. doi: 10.3389/fimmu.2021.806529. eCollection 2021.

T-cell effector pathways in allergic diseases: transcriptional mechanisms and therapeutic targets.

J Allergy Clin Immunol. 2008 Apr;121(4):812-23; quiz 824-5. doi: 10.1016/j.jaci.2008.02.025.

Transcriptional regulation in helper versus cytotoxic-lineage decision.

Curr Opin Immunol. 2009 Apr;21(2):127-32. doi: 10.1016/j.coi.2009.03.012. Epub 2009 Apr 8.

Encoding stability versus flexibility: lessons learned from examining epigenetics in T helper cell differentiation.

Curr Top Microbiol Immunol. 2012;356:145-64. doi: 10.1007/82_2011_141.

Establishing the follicular helper identity.

Immunity. 2009 Sep 18;31(3):450-2. doi: 10.1016/j.immuni.2009.08.017.

Lineage re-commitment of CD4CD8αα intraepithelial lymphocytes in the gut.

BMB Rep. 2016 Jan;49(1):11-7. doi: 10.5483/BMBRep.2016.49.1.242.

Can polyamine metabolism in T helper cell lineage commitment be a new target in allergy research?

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