一例3岁儿童使用双氯芬酸栓剂后发生过敏性休克的病例报告，经连续检测类胰蛋白酶和嗜碱性粒细胞活化试验确诊
A Case Report of a 3-Year-Old Child With Anaphylactic Shock After a Diclofenac Suppository Confirmed by Serial Tryptase and a Basophil Activation Test.
作者信息
Huang Wun-Yan, Chiu Tsu-Man, Kuo Su-Feng, Chung Wen-Hung, Tsai Yi-Giien
机构信息
Department of Pediatric Emergency Medicine, Children Hospital, China Medical University, Taichung, Taiwan.
Department of Medicine, School of Medicine, China Medical University, Taichung, Taiwan.
出版信息
Front Pediatr. 2022 Feb 17;9:802715. doi: 10.3389/fped.2021.802715. eCollection 2021.
Diclofenac is one of the most commonly used non-steroidal anti-inflammatory drug (NSAID) agents for fever management by general practitioners. Anaphylaxis due to suppository of diclofenac sodium (Voltaren) is extremely rare in children. We report the case of a 3-year-old girl with anaphylactic shock after a diclofenac suppository with confirmation by serial tryptase and a basophil activation test.
双氯芬酸是全科医生用于治疗发热时最常用的非甾体抗炎药（NSAID）之一。双氯芬酸钠栓剂（扶他林）引起的过敏反应在儿童中极为罕见。我们报告了一名3岁女孩在使用双氯芬酸栓剂后发生过敏性休克的病例，通过连续检测类胰蛋白酶和嗜碱性粒细胞活化试验得以确诊。
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