Grand River Regional Cancer Centre, 835 King St. W., Kitchener, ON N2G1G3, Canada.
Juravinski Cancer Center, Hamilton Health Sciences Center, 699 Concession St., Hamilton, ON L8V5C2, Canada.
Curr Oncol. 2022 Mar 9;29(3):1828-1839. doi: 10.3390/curroncol29030150.
Lung cancer is the leading cause of cancer death in Canada and a significant cause of morbidity for patients and their loved ones. There have been rapid advances in preventing, screening and treating this disease. Here, we present a contemporary review of treatment of non-small cell lung cancer in Canada based on current best practices. The focus of this review is to highlight recent data in screening for lung cancer, management of patients with early and locally-advanced non-small cell lung cancer, as well as management of patients with metastatic disease. There is a special focus on the incorporation of immunotherapy into practice and its associated toxicities.
肺癌是加拿大癌症死亡的主要原因,也是患者及其亲人发病率的重要原因。在预防、筛查和治疗这种疾病方面已经取得了快速进展。在这里,我们根据当前的最佳实践,对加拿大的非小细胞肺癌治疗进行了当代综述。本综述的重点是强调最近在肺癌筛查、早期和局部晚期非小细胞肺癌患者管理以及转移性疾病患者管理方面的数据。特别关注将免疫疗法纳入实践及其相关毒性。