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老年人感觉障碍与抑郁症状的纵向关系:功能限制的中介作用。

Longitudinal relationship between sensory impairments and depressive symptoms in older adults: The mediating role of functional limitation.

机构信息

Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.

NHC Key Lab of Health Economics and Policy Research, Shandong University, Jinan, China.

出版信息

Depress Anxiety. 2022 Aug;39(8-9):624-632. doi: 10.1002/da.23266. Epub 2022 May 11.

Abstract

BACKGROUND

The underlying mechanism between sensory impairments (SIs) and depressive symptoms among Chinese older adults is not well understood. This study aims to explore the mediating role of functional limitation on the longitudinal relationship between SIs and depressive symptoms among older adults in China.

METHODS

A total of 4130 older adults who participated in the 3-year follow-up China Health and Retirement Longitudinal Study (CHARLS) were included in the analysis. The hierarchical multiple linear regression model and nonparametric bootstrapping method were employed to explore the relationship between SIs and depressive symptoms, and the mediating role of functional limitation in this link.

RESULTS

The prevalence of self-reported hearing impairment (HI) only, vision impairment (VI) only, and dual sensory impairment (DSI) at baseline were 5.7%, 22.2%, and 58.6%, respectively. After adjusting for controlling variables, older adults with DSI had significantly higher levels of depressive symptoms compared with those without SIs at baseline (β = .07, p = .005). The magnitude of mediation effect from DSI to depressive symptoms via functional limitation was a*b = 0.060 (BCa 95% confidence interval: 0.031-0.094).

CONCLUSIONS

Functional limitation partially mediated the relationship between DSI and depressive symptoms among Chinese older adults. Interventions of DSI and functional limitation should be included in depressive symptoms prevention among older adults in China.

摘要

背景

中国老年人的感觉障碍(SIs)和抑郁症状之间的潜在机制尚不清楚。本研究旨在探讨功能限制对中国老年人 SIs 和抑郁症状之间纵向关系的中介作用。

方法

共有 4130 名参加了 3 年随访的中国健康与退休纵向研究(CHARLS)的老年人被纳入分析。采用分层多元线性回归模型和非参数 bootstrap 方法探讨 SIs 和抑郁症状之间的关系,以及功能限制在这一环节中的中介作用。

结果

基线时,自我报告的听力障碍(HI)、视力障碍(VI)和双重感觉障碍(DSI)的患病率分别为 5.7%、22.2%和 58.6%。在调整了控制变量后,与无 SIs 的老年人相比,DSI 的老年人在基线时的抑郁症状水平显著更高(β = .07,p = .005)。从 DSI 通过功能限制到抑郁症状的中介效应大小为 a*b = 0.060(BCa 95%置信区间:0.031-0.094)。

结论

功能限制部分中介了中国老年人 DSI 和抑郁症状之间的关系。在中国,应将 DSI 和功能限制的干预措施纳入老年人抑郁症状预防中。

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