Department of Obstetrics and Gynecology Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, New York, USA.
Department of Obstetrics, Charité - University Medicine Berlin, Berlin, Germany.
J Perinat Med. 2022 Sep 20;51(1):34-38. doi: 10.1515/jpm-2022-0361. Print 2023 Jan 27.
COVID-19 is caused by the 2019 novel coronavirus (2019-nCoV). The first cases of COVID-19 were identified in December 2019, and the first United States (US) case was identified on January 20th, 2020. Since then, COVID-19 has spread throughout the world and was declared a pandemic by the WHO on March 11, 2020. As of July 2022, about 90 million persons have been infected with COVID-19 in the US, and there have been over 1 million deaths There have been 224,587 pregnant patients infected with COVID-19, and 34,527 were hospitalized. Pregnancy increases the risk of severe disease associated with COVID-19 and vaccinated patients are significantly less likely to develop severe disease. Adverse pregnancy and neonatal outcomes are more common among women infected with SARS-CoV-2 during pregnancy, especially among those with severe disease, and vaccination also protects the newborn infant. The intrauterine transmission of SARS-CoV-2 appears to be rare. COVID-19 vaccinations and booster shots in pregnancy are safe. In addition, the available data suggest that vaccination during pregnancy is associated with the transmission of SARS-CoV-2 antibodies to the fetus. The vaccination of lactating women is associated with high levels of SARS-CoV-2 antibodies in the breast milk. It is important that with future pandemics the concept of vaccine recommendations in pregnancy should be made early on to prevent maternal, fetal, and neonatal morbidity and mortality. Physicians and other healthcare professionals should strongly recommend COVID-19 vaccination to patients who are pregnant, planning to become pregnant, and to those who are breastfeeding.
新型冠状病毒病(COVID-19)由 2019 年新型冠状病毒(2019-nCoV)引起。COVID-19 首例病例于 2019 年 12 月确认,美国首例病例于 2020 年 1 月 20 日确认。此后,COVID-19 在全球范围内传播,并于 2020 年 3 月 11 日被世界卫生组织宣布为大流行。截至 2022 年 7 月,美国约有 9000 万人感染了 COVID-19,有超过 100 万人死亡。有 224587 名孕妇感染了 COVID-19,其中 34527 人住院。COVID-19 会增加与感染相关的严重疾病风险,而接种疫苗的患者发生严重疾病的可能性明显降低。在感染 SARS-CoV-2 的孕妇中,妊娠和新生儿不良结局更为常见,尤其是在病情严重的孕妇中,接种疫苗也可以保护新生儿。SARS-CoV-2 的宫内传播似乎很少见。COVID-19 疫苗接种和加强针在妊娠期间是安全的。此外,现有数据表明,妊娠期间接种疫苗与将 SARS-CoV-2 抗体传递给胎儿有关。哺乳期妇女接种疫苗与母乳中 SARS-CoV-2 抗体水平较高有关。重要的是,在未来的大流行中,应尽早提出妊娠期间疫苗接种建议,以预防母婴、胎儿和新生儿发病率和死亡率。医生和其他医疗保健专业人员应强烈建议孕妇、计划怀孕的妇女和哺乳期妇女接种 COVID-19 疫苗。