Vikram Amit, Callahan Mary Tl, Woolston Joelle W, Sharma Manan, Sulakvelidze Alexander
Intralytix, Columbia, MD, United States.
Intralytix, Columbia, MD, United States.
Curr Opin Biotechnol. 2022 Dec;78:102805. doi: 10.1016/j.copbio.2022.102805. Epub 2022 Sep 23.
Foodborne pathogen contamination causes approximately 47 million cases of foodborne illness in the United States and renders thousands of pounds of food products inedible, aggravating the already dire situation of food loss. Reducing foodborne contamination not only improves overall global public health but also reduces food waste and loss. Phage biocontrol or phage-mediated reduction of bacterial foodborne pathogens in various foods has been gaining interest recently as an effective and environmentally friendly food-safety approach. Consequently, several commercial phage-based food-safety products have been developed and are increasingly implemented by the food industry in the United States. This review focuses on the use of phage biocontrol in mitigating bacterial pathogen contamination in various food products with a special emphasis on applications to fresh produce.
食源性病原体污染在美国导致约4700万例食源性疾病病例,并使数千磅食品无法食用,加剧了本就严峻的食物损失状况。减少食源性污染不仅能改善全球总体公共卫生状况,还能减少食物浪费和损失。作为一种有效且环保的食品安全方法,噬菌体生物防治或噬菌体介导减少各类食品中食源性病原体的研究近来备受关注。因此,美国已开发出多种基于噬菌体的商业食品安全产品,食品行业也越来越多地采用这些产品。本综述重点关注噬菌体生物防治在减轻各类食品中细菌病原体污染方面的应用,尤其着重于其在新鲜农产品中的应用。