神经系统类器官和类器官集合体命名共识。
A nomenclature consensus for nervous system organoids and assembloids.
机构信息
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute and Bio-X, Stanford University, Stanford, CA, USA.
出版信息
Nature. 2022 Sep;609(7929):907-910. doi: 10.1038/s41586-022-05219-6. Epub 2022 Sep 28.
Abstract
Self-organizing three-dimensional cellular models derived from human pluripotent stem cells or primary tissue have great potential to provide insights into how the human nervous system develops, what makes it unique and how disorders of the nervous system arise, progress and could be treated. Here, to facilitate progress and improve communication with the scientific community and the public, we clarify and provide a basic framework for the nomenclature of human multicellular models of nervous system development and disease, including organoids, assembloids and transplants.
摘要
自组织的三维细胞模型来源于人类多能干细胞或原代组织，具有深入了解人类神经系统如何发育、使其具有独特性的潜能，以及了解神经系统疾病如何产生、进展和治疗。在这里，为了促进进展并改善与科学界和公众的沟通，我们阐明并提供了神经系统发育和疾病的人类多细胞模型命名法的基本框架，包括类器官、组合体和移植。
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