College of Optometry, Western University of Health Sciences, Pomona, CA 91766, USA.
EyePromise, LLC, Chesterfield, MO 63005, USA.
Nutrients. 2022 Sep 27;14(19):4005. doi: 10.3390/nu14194005.
Digital eye strain is a complex, multifactorial condition that can be caused by excessive screen time exposure to various electronic devices such as smartphones, tablets, e-readers, and computers. Current literature suggests oxidative damage concomitant with a chronic pro-inflammatory state represent significant etiopathogenic mechanisms. The present review aims to discuss the potential dietary role for micronutrients with nutraceutical properties to ameliorate various ocular and vision-related symptoms associated with digital eye strain. For ocular surface dysfunction, enhanced anti-inflammatory benefits with omega-3 polyunsaturated fatty acids have been well documented for treatment of dry eye disease. The anti-oxidative and immunosuppressive properties of anthocyanin phytochemicals may also confer protective effects against visually induced cognitive stress and digital asthenopia. Meanwhile, nutraceutical strategies involving xanthophyll macular carotenoids demonstrate enhanced cognitive functioning and overall visual performance that aids digital eye strain. Collectively, preliminary findings seem to offer a strong line of evidence to substantiate the need for additional randomized controlled trials aimed at treating digital eye strain with adjunctive nutraceutical strategies. Further RCT and comparisons on commercially available nutritional supplements are needed to quantify the clinical benefits.
数字眼疲劳是一种复杂的、多因素的疾病,可能由过度暴露于各种电子设备(如智能手机、平板电脑、电子阅读器和计算机)引起。目前的文献表明,氧化损伤伴随着慢性炎症状态,是重要的发病机制。本综述旨在讨论具有营养特性的微量营养素在改善与数字眼疲劳相关的各种眼部和视力相关症状方面的潜在饮食作用。对于眼表面功能障碍,ω-3 多不饱和脂肪酸具有增强的抗炎作用,已被充分证明可治疗干眼症。花青素类植物化学物质的抗氧化和免疫抑制特性也可能对视觉诱导的认知应激和数字视疲劳提供保护作用。同时,涉及黄斑叶黄素类胡萝卜素的营养策略显示出增强的认知功能和整体视觉表现,有助于缓解数字眼疲劳。总的来说,初步研究结果似乎提供了强有力的证据,证明需要进行更多的随机对照试验,以辅助营养策略来治疗数字眼疲劳。需要进一步的 RCT 和对市售营养补充剂的比较,以量化其临床益处。