1Division of Child Neurology, Department of Pediatrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2Faculty of Teacher Education, University of Zagreb, EpiCARE Croatia, Zagreb, Croatia; 3Department of Pediatrics, Osijek University Hospital Centre, Osijek, Croatia.
Acta Clin Croat. 2021 Dec;60(Suppl 3):25-30. doi: 10.20471/acc.2021.60.s3.03.
Posterior cortex seizures have a complex semiologic presentation that is especially challenging in the pediatric population. Therefore, using clinical presentation in localizing ictal involvement is not sufficient in children, thus making this type of epilepsy quite under-recognized. As most of the ictal symptoms are subjective and could well be overshadowed by symptoms arising from adjacent cortices, primarily temporal and central ones, it is necessary not to overlook this large source of pharmacoresistant epilepsies. The parietal lobe as part of an extensive synaptic network is a great imitator, thus quite often producing inaccurate localization readings on scalp electroencephalography (EEG) due to very scattered interictal discharges and uninformative ictal recordings. Using direct cortical recordings in delineating the epileptogenic zone is helpful in some cases but even highly experienced epileptologists may erroneously interpret some features as arising from other localizations, especially the frontal lobe. Epilepsy surgery from the posterior quadrant is still quite rare and relatively unsuccessful, especially in non-lesional epilepsies due to elaborate mechanisms of connectivity, misleading semiology, and non-localizing EEG recordings, possibly due to insufficiency of parietal cortex synchronicity. Applying the aforementioned to the pediatric age makes it perhaps the most difficult challenge for a pediatric epileptologist.
后部皮层发作具有复杂的症状表现,在儿科人群中尤其具有挑战性。因此,在儿童中,仅根据临床表现来定位发作起源是不够的,这使得这种类型的癫痫发作被严重低估。由于大多数发作症状是主观的,很容易被来自相邻皮层(主要是颞叶和中央区)的症状所掩盖,因此不应忽视这种潜在的耐药性癫痫的巨大来源。顶叶作为广泛的突触网络的一部分,是一个很好的模仿者,因此由于发作间期放电非常分散且发作期记录无信息,头皮脑电图(EEG)常常难以准确定位。在某些情况下,使用直接皮层记录来描绘致痫区是有帮助的,但即使是经验丰富的癫痫专家也可能错误地将某些特征解释为源自其他部位,尤其是额叶。来自后象限的癫痫手术仍然相当罕见且相对不成功,尤其是在非病变性癫痫中,这是由于连接机制复杂、误导性的症状表现和非定位性 EEG 记录,可能是由于顶叶皮质同步性不足所致。将上述内容应用于儿科年龄,对于儿科癫痫专家来说,这可能是最具挑战性的问题。